Phytochemical Screening and Free Radical Scavenging Potential of Mentha piperita L

Jump To References Section

Authors

  • Department of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore-641 043, Tamil Nadu ,IN
  • Department of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore-641 043, Tamil Nadu ,IN
  • Department of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore-641 043, Tamil Nadu ,IN

DOI:

https://doi.org/10.21048/IJND.2021.58.S1.27540

Keywords:

Mentha Piperita L., Antioxidant, Free Radical Scavenging, Flavonoids, Therapeutic Properties, Reducing Power Ability

Abstract

The study investigated the phytochemical compounds and the free radical scavenging potential of Mentha piperita L. Four solvents namely methanol, ethanol, chloroform and water were taken for the extraction of Mentha piperita L. (Peppermint). Preliminary phytochemical analysis was done using the standard protocol. Further, Mentha piperita L. was assessed for the free radical scavenging activity against four radicals namely DPPH, FRAP, hydrogen peroxide and the reducing power ability. Among all the solvents used, methanol extract exhibited the maximum extractive index. The phytochemical screening detected the occurrence of compounds such as flavonoids, carbohydrates, terpenoids, alkaloids, phenols, tannins and quinones. The free radical scavenging activity showed a maximum scavenging power in the methanol extract with increase in concentration. The scavenging efficacy of DPPH, FRAP and hydrogen peroxide were 90.33, 81.52 and 91.38% respectively at 60 μg/ml. Similarly, the reducing power showed the highest at the dose of 60 μg/ml. These findings demonstrated that the Mentha piperita L. has rich phytochemical resources, which act as a potent antioxidant species. Further studies on the therapeutic properties of this plant in animal and human models will resolve its potential for the treatment of lifestyle disorders.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Published

2021-05-18

How to Cite

P., V., E., D., & K.S., S. (2021). Phytochemical Screening and Free Radical Scavenging Potential of <i>Mentha piperita</i> L. The Indian Journal of Nutrition and Dietetics, 58(S1), 73–80. https://doi.org/10.21048/IJND.2021.58.S1.27540

Issue

Section

Original Articles

 

References

Bagul, M.S. Phytochemical evaluation and free radical scavenging properties of rhizome of Bergeniaciliata (Haw) Sternb. J. Natu. Remed., 2003, 3, 83-89.

Cheng, H.Y., Lin, T.C., Yu, K.H., Yang, C.M. and Lin, C.C. Antioxidant and free radical scavenging activities of Terminalia chebula. Biologi. Pharmaceu. Bull., 2003, 26, 1331-1335. DOI: https://doi.org/10.1248/bpb.26.1331

Ozsoy, N., Can, A., Yanardag, R. and Akev, N. Antioxidant activity of Smilax excelsa L. leaf extracts. Fd. Chem.., 2008, 110, 571-583. DOI: https://doi.org/10.1016/j.foodchem.2008.02.037

Wu, S.J. and Ng, L.T. Antioxidant and free radical scavenging activities of wild bitter melon (Momordicacharantia Linn. var. abbreviata Ser.) in Taiwan. LWT-Fd. Sci. Technol., 2008, 41, 323-330. DOI: https://doi.org/10.1016/j.lwt.2007.03.003

Mozaffarian, V. Encyclopedia of Iranian plants. Farhang Moaser Publication, Tehran, Iran, 1996, 671.

Singh, R., Shushni, M.A. and Belkheir, A. Anti-bacterial and antioxidant activities of Mentha piperita L., Arab. J. Chem., 2015, 8, 322-328 DOI: https://doi.org/10.1016/j.arabjc.2011.01.019

Iscan, G., Kirimer, N., Kurkcuoglu, M., Baser, H.C. and Demirci, F. Anti-microbial screening of Mentha piperita essential oils. J. Agri. Fd. Chem.., 2002, 50, 3943-3946. DOI: https://doi.org/10.1021/jf011476k

Moreno, L., Bello, R., Primo-Yúfera, E. and Esplugues, J. Pharmacological properties of the methanol extract from Menthasuaveolens Ehrh. Phytothera. Res., 2002, 16, 10-13. DOI: https://doi.org/10.1002/ptr.744

de Sousa, A. A. S., Soares, P. M. G., de Almeida, A. N. S., Maia, A. R., de Souza, E. P. and Assreuy, A. M. S. Antispasmodic effect of Mentha piperita essential oil on tracheal smooth muscle of rats. J. Ethnopharmacol., 2010, 130, 433-436. DOI: https://doi.org/10.1016/j.jep.2010.05.012

Samarth, R.M., Panwar, M., Kumar, M. and Kumar, A. Protective effects of Mentha piperita Linn on benzo [a] pyrene-induced lung carcinogenicity and mutagenicity in Swiss albino mice. Mutagene., 2006, 21, 61-66. DOI: https://doi.org/10.1093/mutage/gei075

Hoffmann, B.G. and Lunder, L.T. Flavonoids from Mentha piperita leaves. Planta Med., 1984, 50, 361-361. DOI: https://doi.org/10.1055/s-2007-969736

Sokovic, M.D., Vukojevic, J., Marin, P.D., Brkic, D.D., Vajs, V. and Van Griensven, L.J. Chemical composition of essential oilsof thymus and menthe species and their antifungal activities. Molecu., 2009, 14, 238-249. DOI: https://doi.org/10.3390/molecules14010238

Peeyush, K., Sapna, M., Anushree, M. and Santosh, S. Insecticidal properties of Mentha species: a review. Industrial Crops and Products, 2011, 34, 802-817. DOI: https://doi.org/10.1016/j.indcrop.2011.02.019

Krishnaswamy, K. and Raghuramulu, N. Bioactive phytochemicals with emphasis on dietary practices. Ind. J. Med. Res., 1998, 108, 167-181.

Zheng, W. and Wang, S.Y. Antioxidant activity and phenolic compounds in selected herbs. J. Agri. Fd. Chem.., 2001, 49, 5165-5170. DOI: https://doi.org/10.1021/jf010697n

Raman, N. Phytochemical Technique. New Indian Publishing Agencies: New Delhi, 2006, 19.

Mensor, L.L., Menezes, F.S., Leití£o, G.G., Reis, A.S., Santos, T.C. D., Coube, C.S. and Leití£o, S.G. Screening of Brazilian plant extracts for antioxidant activity by the use of DPPH free radical method. Phytothera. Res., 2001, 15, 127-130. DOI: https://doi.org/10.1002/ptr.687

Dehghan, G. and Khoshkam, Z. Tin (II)-quercetin complex: Synthesis, spectral characterisation and antioxidant activity. Fd. Chem., 2012, 131, 422-426. DOI: https://doi.org/10.1016/j.foodchem.2011.08.074

Ruch, R.J., Cheng, S.J. and Klaunig, J.E. Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogen., 1989, 10, 1003-1008. DOI: https://doi.org/10.1093/carcin/10.6.1003

Oyaizu, M. Studies on product of browning reaction prepared from glucosamine. Jap. J. Nutr., 1986, 44, 307-315. DOI: https://doi.org/10.5264/eiyogakuzashi.44.307

Pramila, D.M., Xavier, R., Marimuthu, K., Kathiresan, S., Khoo, M.L., Senthilkumar, M. and Sreeramanan, S. Phytochemical analysis and antimicrobial potential of methanolic leaf extract of peppermint (Menthapiperita: Lamiaceae). J. Med. Plants Res., 2012, 6, 331-335. DOI: https://doi.org/10.5897/JMPR11.1232

Farnad, N., Heidari, R. and Aslanipour, B. Phenolic composition and comparison of antioxidant activity of alcoholic extracts of Peppermint (Mentha piperita). J. Fd. Measure. Characterizat., 2014, 8, 113-121. DOI: https://doi.org/10.1007/s11694-014-9171-x

Shimada, K., Fujikawa, K., Yahava, K. and Nakamura, T. Antioxidative properties of xanthan on the autoxidation of Soybean oil in cyclodextrin emulsion. J. Agri. Fd. Chem., 1992, 40, 945-948. DOI: https://doi.org/10.1021/jf00018a005

Dorman, H.D., Koşar, M., Başer, K.H.C. and Hiltunen, R. Phenolic profile and antioxidant evaluation of Mentha x piperita L. (peppermint) extracts. Natural product communications, 2009, 4. DOI: https://doi.org/10.1177/1934578X0900400419

Kahkonen, M.P., Hopia, A.I., Vuorela, H.J., Rauha, J.P., Pihlaja, K., Kujala, T.S. and Heinonen, M. Antioxidant activity of plant extracts containing phenolic compounds. J. Agri. Fd. Chem.., 1999, 47, 3954-3962. DOI: https://doi.org/10.1021/jf990146l