Nutritional Metabolomics and Nutrigenomics their Role in Breast Cancer: An Overview
Authors
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Department of Biochemistry, Biotechnology and Bioinformatics Avinashilingam Institute for Home Science and Higher Education for Women Coimbatore - 641 043 ,IN
Sumathi S. -
Department of Biochemistry, Biotechnology and Bioinformatics Avinashilingam Institute for Home Science and Higher Education for Women Coimbatore - 641 043 ,INVarghese Angel Chalos
DOI:
https://doi.org/10.21048/IJND.2024.61.2.43710Keywords:
Nutrition, breast cancer, nutrigenomics, gut microbiota, cancer, phytonutrientsAbstract
Breast cancer physiology is still being studied, and a patient's diet may have an impact on both their risk of developing the disease and how they respond to treatment once they are diagnosed. Nutritional treatments are essential public health initiatives since good nutrition plays a noteworthy role in illness prevention. In this postgenomic medicineera, the combination of nutritional, genomic, and proteomic disciplines has given rise to nutrigenomics and nutriproteomics. In particular, nutrigenomics and nutriproteomics concentrate on the interactions between nutrients and the human genome and proteome, respectively, and offer intuitions into the role that nutrition plays in the progression of cancer. A deeper understanding of nutrition and its underlying causes is anticipated to come from additional omics disciplines such as metabonomics, interactomics, and microbiomics. For the creation of individualised diets for women at risk of breast cancer, these domains offer a hitherto unheard-of potential. It will assist in determining a person's unique nutritional needs based on their genetic makeup, a personalised diet, and the relationship between diet and chronic diseases like cancer, opening up new perspectives on the complexity of breast cancer and paving the way for better management of the disease.
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