Exposure Assessment of Artificial Sweeteners among Type 2 Diabetic, Overweight and Obese Individuals
DOI:
https://doi.org/10.21048/ijnd.2016.53.3.5297Keywords:
Artificial Sweeteners, Diabetes, Aspartame, Overweight and Obesity.Abstract
In recent years consumption of artificially sweetened foods and beverages became popular in India, with the regulatory formulations to use them in selected foods; their inclusion especially in sweets, biscuits and beverages has increased. There are many concerns rising regarding their safety and is becoming an area of controversy. So an exposure assessment has been carried out to evaluate intake levels among type II diabetic, overweight and obese individuals. A cross-sectional study design was applied and a food frequency questionnaire was used to obtain the information on consumption pattern. Range, standard deviation and mean daily intake levels were calculated and the values were compared with an appropriate Acceptable Daily Intake (ADI). Results indicated that, the mean daily intake levels of aspartame (0.85±0.75) were found to be high among type 2 diabetic individuals whereas sucralose (0.41±0.41) and acesulfame-k (0.07±0.02) were high among overweight group. There was a significant difference (p<0.0001) observed in intake levels among both groups and all the sweeteners were found to be well within the ADI levels.Downloads
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References
Ahmad, S., Farooq, A.K., Abdul, H. and Muhammad, S.N. A Review on potential toxicity of artificial sweeteners vs. safety of stevia: A natural bio-sweetener J. Bio, Agric. Healthcare., 2014, 4, 137-147.
JECFA (Joint FAO/WHO Expert Committee on Food Additives), Neotame – food additive series 52, First draft prepared by Dr P.J. Abbott, 2004.
Sam Kacew., Taylor and Francis. Lu's Basic Toxicology: Fundamentals, target organs and risk assessment. ADI: LU, Frank C., 2002, 8, 364 - 415.
FDA (Food and Drug Administration), FDA's response to European Aspartame Study. [Last accessed on 2011 Feb 4]. Available from: http://www.fda.gov/bbs/topics/NEWS/2006/ NEW01369.html.
FSSAI, Food safety and standards authority of India, regulations 2011 part I and part II, prohibition and restriction on sales. [Last accessed on 2015 Feb 11].
Bellisle, F. and Drewnowski, A. Intense sweeteners, energy intake and the control of body weight. Eur. J. Clin. Nutr., 2007, 61, 691–700.
Rejeanne, G., Kristy, L. and Catherine, J. Canadian diabetes association national nutrition committee technical review: non-nutritive intense sweeteners in diabetes management. Canada J. diab., 2004, 28, 385-399.
DeNoon, Daniel, J. Drink more diet soda, gain more weight? Overweight risk soars 41% with each daily can of diet soft drink, Web MD Medical News (2005) [Last accessed on 2015 Feb 11].
Swithers, S.E. and Davidson, T.L. A role for sweet taste: Calorie predictive relations in energy regulation by rats. Behav. Neurosci., 2008, 122, 161–173.
Mathur, P. and Arushi Jain. Intake of processed foods and selected food additives among teenagers of 13-19 years of Delhi, India: Asian J. multidiscipl. stud., 2014, 4, 64-77.
Tripathi, M., Khanna, S.K. and Das, M. Usage of saccharin in food products and its intake by the population of Lucknow, India. J. Fd. Additives. Contaminants, 2006, 23, 1270-1275.
Llback, N.G., Alzin, M., Jahrl, S., Enghardt-Barbieri, H. and Busk, L. Estimated intake of the artificial sweeteners acesulfame-k, aspartame, cyclamate and saccharin in a group of Swedish diabetics. J. Fd. Addit. Contam., 2003, 20, 99-114.
Poonam singhal and Pulkit Mathur, Availability and consumption pattern of artificial sweeteners among diabetics, overweight individuals and college girls in Delhi. Ind. J. Dietet., 2008, 45, 26.
Leclercq, C., Berardi, D., Sorbillo, M.R. and Lambe, J. Intake of saccharin, aspartame, acesulfame- K and cyclamate in Italian teenagers: present levels and projections. J. Fd. Addit. Contam., 1999, 16, 99–109.
Arcella, D., Le Donne, C., Piccinelli, R. and Leclercq, C. Dietary estimated intake of intense sweeteners by Italian teenagers. Present levels and projections derived from the INRANRM2001 food survey. J. Fd. Chem. Toxicol., 2004, 42, 677–685.
Wilson, L.A., Wilkinson, K., Crews, H.M., Davies, A.M., Dick, C.S and Dumsday, V.L. Urinary monitoring of saccharin and acesulfame-K as biomarkers of exposure to these additives. J. Fd. Addit. Contam., 1999, 16, 227–238.
Bemrah. N., Leblanc, J.C. and Volatier, J.L. Assessment of dietary exposure in the French population to 13 selected food colours, preservatives, antioxidants, stabilizers, emulsifiers and sweeteners. J. Fd. Addit. Contam., 2008, 1, 2–14.
Serra-Majem, L., Bassas, L., Garcia-Glosas, R., Ribas, L., Ingles, C., Casals, I., Saavedra, P. and Renwick, A.G. Cyclamate intake and cyclohexylamine excretion are not related to male fertility in humans. J. Fd. Addit. Contam., 2003, 20, 1097–1104.
Leth, T., Jensen, U., Fagt, S. and Andersen, R. Estimated intake of intense sweeteners from non-alcoholic beverages in Denmark, 2005. J. Fd. Addit. Contam., 2008, 25, 662–668.
Garnier-sagne, I., Leblanc, J.C. and Verger, P. Calculation of the intake of three intense sweeteners in young insulin-dependent diabetics. J. Fd. Chem. Toxicol., 2001, 39, 745-749.
Christina, R., Boullata, J. and McCauley, L.A. The potential toxicity of artificial sweeteners. Work place, Health and Safety, 2008, 56, 251-259.