Antiulcer Activity of Aqueous Extract of Basella rubra in Albino Rats

Abstract

Objective: To evaluate the antiulcer activity of aqueous extract of Basella rubra. Materials and method: Aqueous extract of the leaves of Basella rubra was prepared and antiulcer activity was studied on ethanol and pylorus ligated induced gastric ulcers in rats. Results: Aqueous extract of the leaves of Basella rubra (10 and 20mg/kg p.o.) showed significant and dose-dependent antiulcer activity against ethanol and pylorus ligated induced ulcer in rats. Study was compared with ranitidine (50 mg/kg p.o.) as standard drug. Conclusion: The present results indicate the potential of aqueous extract of Basella rubra in the treatment of gastric ulcers.