Isolation and Characterization of Bioactive Moiety from Leaf Extract of Ipomoea mauritiana and Evaluation of Anti-Inflammatory Activity by Carrageenan Induced Rat Paw Edema Test

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Authors

  • S. Mahadeva Murthy
     Department of Microbiology, Yuvaraja's College, University of Mysore, Mysuru - 570005, Karnataka, India ,IN
  • N. Lakshmi Devi
     Department of Studies in Microbiology, Manasa Gangothri, University of Mysore, Mysuru - 570006, Karnataka, India ,IN
  • M. K. Ramakrishna
     Drosophila Stock Centre, Department of Studies in Zoology, Manasa Gangothri, University of Mysore, Mysuru - 570006, Karnataka, India ,IN

DOI:

https://doi.org/10.18311/jnr/2017/18176

Keywords:

Anti Inflammatory Activity, Carrageenan Induced Rat Paw Edema Column, Chromatography, Ipomoea Mauritiana

Abstract

Ipomoea mauritiana Jacq. is a member of family Convolvulaceae and commonly called as Ksheervidari is widely used in various traditional medicines for the treatment of many diseases. In the present work the column fractions of leaf extracts of I. mauritiana obtained by Soxhlet exrtaction was subjected to TLC, column chromatography, HPLC and liquid chromatography and mass spectroscopy (LC-MS). The compounds like caffeic acid and β-amyric acetate were tentatively identified to be present in one of the purified fraction. The column fraction was also tested for anti-inflammatory activity by carrageenan induced rat paw edema assay. The column fraction tested showed a very good anti inflammatory activity.

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Published

2018-02-19

How to Cite

Murthy, S. M., Devi, N. L., & Ramakrishna, M. K. (2018). Isolation and Characterization of Bioactive Moiety from Leaf Extract of Ipomoea mauritiana and Evaluation of Anti-Inflammatory Activity by Carrageenan Induced Rat Paw Edema Test. Journal of Natural Remedies, 17(3), 80–87. https://doi.org/10.18311/jnr/2017/18176

Issue

Volume 17, Issue 3, July 2017

Section

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