Effect of Bauhinia variegate Bark Extract on Blood Glucose Level in Normal and Alloxanised Diabetic Rats

Abstract

The antidiabetic activity of Ethanol (95%) bark extract of Bauhinia variegata Linn. was evaluated in alloxaninduced diabetic rats. The various parameters like blood glucose, body weight, total cholesterol, triglycerides, high density lipoprotein, insulin, oral glucose tolerance test and histopathology of pancreas were studied. The results were found to be significant antidiabetic by reducing the blood glucose level, improving body weight, attenuating the altered lipid profile toward the normal and by regenerating the Islets of langerhans. Therefore the present study justifies that ethanol extract of Bauhinia variegata exhibits significant antidiabetic activity, so this extract may have Insulin-like properties.