Analyzing the Phytochemical, Anti-ulcer, Anthelmentic and Antioxidant Potentials of Tabernaemontana dichotoma Roxb. ex Wall Seed Extracts

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Authors

  • P. Vishwaprakash Mahadimane
     Department of Studies in Bioscience, University of Mysore, Hassan, Karnataka ,IN
  • S. P. Sharath Chandra
     Department of Biochemistry, Government Science College, Hassan – 573201, Karnataka ,IN

DOI:

https://doi.org/10.18311/jnr/2020/24346

Keywords:

Antioxidant, Anti-ulcer, DPPH, Phytochemicals

Abstract

In the current investigation, phytochemical analysis, antioxidant, anti-ulcer and in vitro anthelmintic studies of Tabernaemontana dichotoma Methanol Extract (TCME) and Aqueous Extract (TCAE) from seeds were evaluated. Phytochemical analysis confirmed the occurrence of various secondary metabolites. Biological evaluation showed a dose dependent response of different extracts of T. dichotoma seeds. Both the extracts showed antioxidant potential. TCME displayed higher degree of H+ K+ ATPase on par with omeprazole, thus confirming the anti-ulcer potential of the plant. TCME also exhibited better wormicidal activity compared to the other extract in both paralysis of earthworms (Pheretimaposthuma), and confirming its role as anthelmentic medicine. The study confirms the anti-ulcer and anthelmentic properties of T. dichotoma seed extracts, with TCME showing higher efficacy.

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Published

2020-06-11

How to Cite

Mahadimane, P. V., & Sharath Chandra, S. P. (2020). Analyzing the Phytochemical, Anti-ulcer, Anthelmentic and Antioxidant Potentials of <i>Tabernaemontana dichotoma Roxb</i>. ex Wall Seed Extracts. Journal of Natural Remedies, 20(2), 89–95. https://doi.org/10.18311/jnr/2020/24346

Issue

Volume 20, Issue 2, April 2020

Section

Research Articles
Crossref
Scopus
Google Scholar
Europe PMC
Received 2019-10-21
Accepted 2020-02-19
Published 2020-06-11

 

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