Antimicrobial, Antioxidant and Anticancer Activity of the Ethanol Extract of Pleurotus ostreatus

Jump To References Section

Authors

  • J. Bindhu
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu ,IN
  • Arunava Das
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu ,IN
  • E. Vihashinee
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu ,IN
  • A. Rubiga
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu ,IN
  • Aswin Edward
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu ,IN
  • R. Eswaran
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu ,IN
  • G. Shanmuga Priya
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu ,IN
  • S. Soundariya
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu ,IN
  • Aileen Rose Edwin
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu ,IN

DOI:

https://doi.org/10.18311/jnr/2020/24382

Keywords:

MTT, DPPH, HL-60 cells, FRAP, GC-MS

Abstract

The current study evaluates antimicrobial, antioxidant and anticancer activity of the ethanol extract of Pleurotus ostreatus. Chemical analysis showed the presence of alcohol, amides, alkanes, ether, phenol and sulphides. Most of the chemical constituents were found to be esters and carboxylic acid derivatives. The extract showed highest resistant against Bacillus cereus. P. ostreatus ethanol extract showed comparable antioxidant activity with ascorbic acid in both DPPH and FRAP method and also showed an IC50 of 39.29 μg/ml against HL60 cells.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Downloads

Published

2020-06-11

How to Cite

Bindhu, J., Das, A., Vihashinee, E., Rubiga, A., Edward, A., Eswaran, R., Shanmuga Priya, G., Soundariya, S., & Rose Edwin, A. (2020). Antimicrobial, Antioxidant and Anticancer Activity of the Ethanol Extract of <i>Pleurotus ostreatus</i>. Journal of Natural Remedies, 20(2), 110–115. https://doi.org/10.18311/jnr/2020/24382

Issue

Volume 20, Issue 2, April 2020

Section

Research Articles
Crossref
Scopus
Google Scholar
Europe PMC
Received 2019-10-29
Accepted 2020-02-19
Published 2020-06-11

 

References

Prasad AS, Bao B, Beck FWJ, Kucuk O, Sarkar FH. Antioxidant effect of zinc in humans. Free Radical Biology Medicine. 2004; 37:1182–90. https://doi.org/10.1016/j.freeradbiomed.2004.07.007 PMid:15451058

Jose N, Ajith TA, Janardhanan KK. Antioxidant, anti-inflammatory and antitumor activities of culinarymedicinal mushroom Pleurotus pufmonanus (Fr.) Quel. (Agaricomycetideae). International Journal of Medicinal Mushrooms. 2002; 4:329–35. https://doi.org/10.1615/ IntJMedMushr.v4.i4.60

Jayakumar T, Ramesh E, Geraldine P. Antioxidant activity of the oyster mushroom Pleurotus ostreatus on CCl 4 -induced liver injury in rats. Food and chemical toxicology. 2016; 44:1989–96. https://doi.org/10.1016/j.fct.2006.06.025. PMid:16914248

Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M. Free radicals, metals and antioxidants in oxidative stress-induced cancer, Chemical Biological Interaction. 2006; 160:1–40. https://doi.org/10.1016/j.cbi.2005.12.009. PMid:16430879

Woldegiorgis AZ, Abate D, Haki GD, Ziegler GR. Antioxidant property of edible mushrooms collected from Ethiopia. Food Chemistry. 2014; 157:30–6. https://doi.org/10.1016/j.foodchem.2014.02.014. PMid:24679748

Michalak A. Phenolic compounds and their antioxidant activity in plants growing under heavy metal stress. Polish Journal of Environmental Studies. 2006; 15:523–30.

Oyetayo VO, Ariyo OO. Antimicrobial and antioxidant properties of Pleurotus ostreatus (Jacq: Fries) cultivated on different tropical woody substrates. Journal of Waste Conversion, Bioproducts and Biotechnology. 2013; 2:28– 32.

Oboh G, Ademosun AO. Characterization of the antioxidant properties of phenolic extracts from some citrus peels. Journal of Food Science and Technology. 2012; 49:729–36. https://doi.org/10.1007/s13197-010-0222-y. PMid:24293692 PMCid:PMC3550823

Vishwakarma P, Singh P, Tripathi NN. In-vitro antioxidant activity and nutritional value of four wild oyster mushroom collected from North-Eastern Part of Uttar Pradesh. Mycosphere. 2017; 8:592–602.

https://doi.org/10.5943/mycosphere/8/4/8

Singh V, Pandey R, Vyas D. Antioxidant potentiality of Pleurotus ostreatus (MTCC142) cultivated on different agro wastes. Asian Journal of Plant Science and Research. 2015; 5:22-7.

Riaz M, Mehmood KT. Selenium in human health and disease. Journal of Postgraduate Medicine. 2012; 26:120–33.