Formulation and Standardization of Polyherbal Antihyperlipidemic Formulation

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Authors

  • Smitha Rani
     Department of Chemistry, VIT University, Vellore – 632014, Tamil Nadu ,IN
  • S. L. Manju
     Department of Chemistry, School of Advanced Sciences, VIT University, Vellore – 632014, Tamil Nadu ,IN

DOI:

https://doi.org/10.18311/jnr/2020/24795

Keywords:

Antihyperlipidemic, HPTLC Profiling, Physico-chemical Parameters, Polyherbal, Standardization
Pharmacuetical Chemistry

Abstract

Hyperlipidemia is a very common medical condition. A fairly less invasive, more effective and efficient method with lower or no side effects to treat Hyperlipidemia are to be developed. Thus, use of traditional herbal medication can be a relevant solution to it. Development of highly standardized Polyherbal formulation with respect to chemical content and therapeutic activity is considered as a valuable approach in the field of herbal industry. Traditional medicine is known for its Polyherbal contents and multicomponent therapeutics for managing health problems. Thus, the present research is focused on to formulate, standardize a polyherbal medicine to treat hyperlipidemia and also compared its chemical contents based on, geographical, seasonal variations using standard physio-chemical parameters such as Ash values, Extractive values, pH, and loss on drying, Particle size analysis and physical analysis of powder formulation. HPTLC fingerprinting, with markers such as Gallic acid, Quercetin, Gymnemic acid, and Mahanine were carried out. In addition, residue analysis such as heavy metal content, microbial load, pesticide analysis, aflotoxin determination were also carried out to strengthen the standardization process and to ensure safety.

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Published

2021-01-22

How to Cite

Rani, S., & Manju, S. L. (2021). Formulation and Standardization of Polyherbal Antihyperlipidemic Formulation. Journal of Natural Remedies, 20(4), 228–239. https://doi.org/10.18311/jnr/2020/24795

Issue

Volume 20, Issue 4, October 2020

Section

Research Articles
Crossref
Scopus
Google Scholar
Europe PMC
Received 2020-01-19
Accepted 2020-09-14
Published 2021-01-22

 

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