Preparation and Exploration of Physical Properties of Calcium based Indian Origin Ayurvedic Medicine-Shankh Bhasma (Marine Drug) as Nanomaterials for its Applications

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Authors

  • Sweta Sinha
     Aryabhatta Centre for Nano Science and Nanotechnology, School of Engineering and Technology, Aryabhatta Knowledge University, Patna – 800001, Bihar ,IN
  • Rakesh Kr. Singh
     Aryabhatta Centre for Nano Science and Nanotechnology, School of Engineering and Technology, Aryabhatta Knowledge University, Patna – 800001, Bihar ,IN
  • Nishant Kumar
     Aryabhatta Centre for Nano Science and Nanotechnology, School of Engineering and Technology, Aryabhatta Knowledge University, Patna – 800001, Bihar ,IN
  • Subhash Pd. Singh
     Department of Chemistry, AN College, Patna, Patliputra University, Patna – 800001, Bihar ,IN
  • Prabhat Kr. Dwivedi
     Aryabhatta Centre for Nano Science and Nanotechnology, School of Engineering and Technology, Aryabhatta Knowledge University, Patna – 800001, Bihar ,IN
  • Rekha Kumari
     Department of Zoology, AN College, Patna and Department of Education, Govt. of Bihar, Patna – 800001, Bihar ,IN

DOI:

https://doi.org/10.18311/jnr/2021/26225

Keywords:

Ayurveda, Marine, Nanomaterials, Physical Properties, Shankh Bhasma
Nanotechnology, Bhasma

Abstract

The objective of the present research is to explore the Physical properties of a marine origin of Indian Ayurvedic medicine (Shankh Bhasma) as nanomaterials for its applications. Shankh Bhasma has been prepared by using the method as mentioned in Ayurvedic text which includes aloe-vera and buttermilk as ingredient. The preparation method was ecofriendly and hazardous chemicals are not used or emitted during preparation. The bhasma are characterized by the modern scientific techniques. X-ray diffraction measurement and Scanning electron microsccopy analysis showed that Bhasma exists as agglomerated nano crystalline materials. Fourier transform infrared spectroscopy measurement reveals the bond stretching during the incineration process and found peaks of carboxylic group, calcium carbonate and calcium hydroxide. The photoluminescence measurement shows a broad spectrum in UV region and one prominent emission peak in the visible region at 405nm. The prepared shankh bhasma was examined on E. coli and found to have no effect. In present research, physical property measurement of shankh bhasma using state of the art techniques of 21st century not only support a foundation for the development of low cost ayurvedic natural marine based materials as nanomedicne but also used in other sectors of science and technology.

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Published

2021-07-06

How to Cite

Sinha, S., Singh, R. K., Kumar, N., Singh, S. P., Dwivedi, P. K., & Kumari, R. (2021). Preparation and Exploration of Physical Properties of Calcium based Indian Origin Ayurvedic Medicine-Shankh Bhasma (Marine Drug) as Nanomaterials for its Applications. Journal of Natural Remedies, 21(3), 225–234. https://doi.org/10.18311/jnr/2021/26225

Issue

Volume 21, Issue 3, July 2021

Section

Research Articles
Crossref
Scopus
Google Scholar
Europe PMC
Received 2020-10-09
Accepted 2021-03-09
Published 2021-07-06

 

References

Vadnare G, Pathan A, Singhai, et al. Characterization of indigenous traditional medicine. Muktashukti Bhasma. Indian J Tradit Knowl. 2013; 12(2013):483– 8.

Chaudhary A. Ayurvedic Bhasma: Nanomedicine of ancient India, its global contemporary perspective. J Biomed Nanotechnol. 2011; 7(2011):68–9. https:// doi.org/10.1166/jbn.2011.1205. PMid:21485807

Palkhiwal S, Sonal R. Engineered nanoparticles: Revisiting safety concerns in light of ethno medicine. Ayu. 2014; 35(3). https://doi.org/10.4103/0974-85 20.153785. PMid:26664232. PMCid:PMC4649566

Nikalje AP. Nanotechnology and its applications in medicine. Med Chem. 2015; 5(2). https://doi. org/10.4172/2161-0444.1000247

Pal D, Sahu CK, Haldar A. Bhasma: The ancient Indian nanomedicine. J Adv Pharm Technol Res. 2014; 5(2014):4–12. https://doi.org/10.4103/2231- 4040.126980. PMid:24696811. PMCid:PMC3960793

Sharma GRPPR. Revisiting the ancient claims of nanomedicine. BAOJ Nanotechnology. 2016; 2(2).

Kumar A, Nair AG, Reddy AV, Garg AN, et. al. Bhasmas: Unique ayurvedic metallic-herbal preparations, chemical characterization. Biol Trace Elem Res. 2006; 109:231–54. https://doi.org/10.1385/ BTER:109:3:231

Srilakshmi D, Shalini TV, Smitha J, et. al. Therapeutic potentials of sudh varga Rasa Dravya vis -A vis Calcium copmpounds a Review. IRJP. 2012; 3(10).

Seth A, Maurya SK , Srivastava A. Formulation development, characterization and estimation of acid neutralization capacity of shankha bhasma tablets for the treatment of dyspepsia. Int J Pharm Pharm Sci. 2014; 6(2):467–9.

Pal D, Sahu CK, Haldar A. Bhasma: The ancient Indian nanomedicine. J Adv Pharm Technol Res. 2014; 5:4. https://doi.org/10.4103/2231-4040.126980. PMid:24696811. PMCid:PMC3960793

Sadeghi M, Husseini MH. A novel method for the synthesis of CaO nanoparticle for the decomposition of sulfurous pollutant. J Appl Chem Res. 2013; 7:39– 49.

Butt AR, Ejaz SJ, Baron C, Ikram M, Ali S, et. al. CaO nanoparticles as a potential drug delivery agent for biomedical applications. Dig J Nanomater. Biostruc10. 2015:799–809. https://doi.org/10.3390/ su11113196

Alavi MA, Morsal A. Ultrasonic-assisted synthesis of Ca(OH)2 and CaO nanostructures. J Exp Nano Sci. 2010:93–105. https://doi.org/10.1080/174580809 03305616

Khan MD, Ahn JW, Nam G. Environmental benign synthesis,characterization and mechanism studies of green calcium hydroxide nano-plates derived from waste oyster shells. J Environ Manag. 2018; 223:947–51. https://doi.org/10.1016/j.jenvman.2018.07.011. PMid:30007890

Praikaew W, Kiatkittipong W, Kiatkittipong K, Laosiripojana N, Viriya-empikul N, Boonyasuwat S, et. al. Synthesis of glycerol carbonate from dimethyl carbonate and glycerol using CaO derived from eggshells. MATEC Web of Conferences; 2018. https://doi.org/10.1051/matecconf/201819203045

Rasheed SP, Shivashankar M. Synthesis and characterization of Shanku bhasma-an anti-ulcer herbomineral formulation. IOP Conf Ser: Mater Sci Eng. 2017. https://doi.org/10.1088/1757-899X/ 263/2/022026

Liu T, Zhu Y, Zhang X, Zhang T, Zhang T, Li X. Synthesis and characterization of calcium hydroxide nanoparticles by hydrogen plasma-metal reaction method. Mater Lett. 2010; 64:2575–7. https://doi. org/10.1016/j.matlet.2010.08.050

Roy A, Bhattacharya J. Microwave assisted synthesis of CaO nanoparticles and use in waste water treatment. Nano Technol. 2011; 3:565–8.

Yang Y, Wang XH, Sun CK, Li LT. Structural and optical properties of ZnO nanoparticles synthesized at different pH Values. Journal of Applied Physics. 2009; 105. https://doi.org/10.1063/1.3121202

Zhiwei P, Guozhang D, Peng C, Qinglin Z, Qiang W, Bingsuo. Synthesis, characterization and optical properties of star-like ZnO nanostructures. Mater Lett. 2010; 64:890. https://doi.org/10.1016/j.matlet. 2010.01.029

Singh RK , Kumar S, Kumar A, Kumar S, Kar M, Tripathi S. Physical properties of an Indian Ayurvedic medicine (Shankh Bhasma) as nanomaterials for its application. Indian J Tradit Knowl. 2019; 18(1):178– 83.

Chivhane S, Savrikar S. Study of physico-chemical properties and antimicrobialactivity of shukti marit haratal bhasma invitro. Journal of Pharmaceutical Research. 2017; 6(2).