The Effect of Traditional Home Remedies on Glycemic Control among People with Type 2 Diabetes Mellitus (T2DM)

Jump To References Section

Authors

  • Department of Physiotherapy, School of Allied Health Sciences, Manipal Academy of Higher Education (MAHE), Manipal - 576104, Karnataka ,IN
  • PU-RCSI School of Medicine, Perdana University, Wisma Chase Perdana, Damansara Heights, Kuala Lumpur - 50490 ,MY
  • PU-RCSI School of Medicine, Perdana University, Wisma Chase Perdana, Damansara Heights, Kuala Lumpur - 50490 ,MY
  • PU-RCSI School of Medicine, Perdana University, Wisma Chase Perdana, Damansara Heights, Kuala Lumpur - 50490 ,MY
  • PU-RCSI School of Medicine, Perdana University, Wisma Chase Perdana, Damansara Heights, Kuala Lumpur - 50490 ,MY
  • Manipal College of Nursing, Manipal, MAHE, Manipal - 576104, Karnataka ,IN
  • Department of Medicine, Medical Superintendent, Dr TMA Pai Hospital and Melaka Manipal Medical College, MAHE, Manipal - 576104, Karnataka, India ,IN

DOI:

https://doi.org/10.18311/jnr/2022/28166

Keywords:

Bittergourd, Fenugreek, Neem, Traditional Home Remedy, Type 2 Diabetes Mellitus
Traditional Home Remedy

Abstract

Traditional home remedy consumption is a typical ancient practice in India. These traditional home remedies are found to have beneficial effects on many chronic conditions. This study was designed to explore the effect of traditional home remedies on glycemic control in people with type 2 Diabetes Mellitus (DM). In this study, 148 type-2 DM patients aged between 35 and 70 of both genders, participated. Among 148 type-2 DM patients, 102 T2DM patients use traditional home remedies along with oral anti-diabetic drugs, while the remaining 46 are non-users. The details of age, duration of type- 2 DM, glycated Hb (HbA1c) values, and use of traditional home remedies were obtained from a cross-sectional survey. The HbA1c value of 7-8% was considered an optimal target glycemic control, and ≤ 7% was considered poor control. A mean and SD were used to represent descriptive statistics. An independent sample test was used to compare the mean HBA1c between the fenugreek users and non-users by considering p<0.05 as statistically significant. The majority of type- 2 DM in our study group used Trigonella foenum-graecum (Fenugreek) (76.47%). A small proportion of our study group is using Azadirachta indica (Indian lilac or neem) (7.84%), Momordica charantia (bitter guard) (3.93%), and Aegle marmelos L. (Bengal quince or bael) (2.94%). The HbA1c levels in the majority of the traditional home remedy users were within the recommended target levels. The mean HbA1c levels of fenugreek non-users were significantly higher (p<0.001) than fenugreek users. In conclusion, our study shows that type-2 DM traditional home remedy users have better glycemic control than non-users. Home remedies are potent natural food sources that can be used with anti-diabetic drugs. However, such a use should be done with the knowledge of treating doctors, which may help to achieve better glycemic control and prevent type-2 DM-related complications.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Downloads

Published

2022-12-16

How to Cite

Matpady, P., Maiya, G. A., Gaundar, N., Shetty, J. K., Bhojaraja, V. S., Anupama, D. S., & Umakanth, S. (2022). The Effect of Traditional Home Remedies on Glycemic Control among People with Type 2 Diabetes Mellitus (T2DM). Journal of Natural Remedies, 22(4), 697–703. https://doi.org/10.18311/jnr/2022/28166

Issue

Section

Short Communication
Received 2021-07-11
Accepted 2022-06-08
Published 2022-12-16

 

References

Ozougwu JC, Obimba KC, Belonwu CD, Unakalamba CB. The pathogenesis and pathophysiology of type 1 and type 2 diabetes mellitus. Journal of Physiology and Pathophysiology. 2013; 4(4):46-57. https://doi.org/10.5897/ JPAP2013.0001 DOI: https://doi.org/10.5897/JPAP2013.0001

Federation ID. IDF diabetes atlas ninth. Dunia: IDF. 2019.

Rowley WR, Bezold C. Creating public awareness: state 2025 diabetes forecasts. Population health management. 2012; 15(4):194-200. https://doi.org/10.1089/pop.2011.0053 DOI: https://doi.org/10.1089/pop.2011.0053

Ramachandran A, Snehalatha C, Shetty AS, Nanditha A. Trends in prevalence of diabetes in Asian countries. World Journal of Diabetes. 2012; 3(6):110. https://doi.org/10.4239/ wjd.v3.i6.110 DOI: https://doi.org/10.4239/wjd.v3.i6.110

Pandey SK, Sharma V. World diabetes day 2018: battling the emerging epidemic of diabetic retinopathy. Indian Journal of Ophthalmology. 2018; 66(11):1652. https://doi. org/10.4103/ijo.IJO_1681_18 DOI: https://doi.org/10.4103/ijo.IJO_1681_18

Gupta M, Prabhu K, Parijatham BO, Kalaiselvi VS, Rajendran SM, Rose J. Prevalence of diabetes mellitus in South India: A retrospective analysis. JIMSA. 2012; 25(4):239-40.

Kahn SE, Cooper ME, Del Prato S. Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future. The Lancet. 2014; 383(9922):1068-83. https://doi.org/10.1016/S0140-6736(13)62154-6 DOI: https://doi.org/10.1016/S0140-6736(13)62154-6

Chen L, Pei JH, Kuang J, Chen HM, Chen Z, Li ZW, Yang HZ. Effect of lifestyle intervention in patients with type 2 diabetes: a meta-analysis. Metabolism. 2015; 64(2):338-47. https://doi.org/10.1016/j.metabol.2014.10.018 DOI: https://doi.org/10.1016/j.metabol.2014.10.018

Pandey MM, Rastogi S, Rawat AK. Indian traditional ayurvedic system of medicine and nutritional supplementation. Evidence-Based Complementary and Alternative Medicine. 2013; 2013. https://doi.org/10.1155/2013/376327 DOI: https://doi.org/10.1155/2013/376327

Gordon A, Buch Z, Baute V, Coeytaux R. Use of ayurveda in the treatment of type 2 diabetes mellitus. Global Advances in Health and Medicine. 2019; 8:2164956119861094. https://doi.org/10.1177/2164956119861094 DOI: https://doi.org/10.1177/2164956119861094

Chang KW, Li J, Yang CH, Shiesh SC, Lee GB. An integrated microfluidic system for measurement of glycated hemoglobin Levels by using an aptamer-antibody assay on magnetic beads. Biosensors and Bioelectronics. 2015; 68:397-403. https://doi.org/10.1016/j.bios.2015.01.027 DOI: https://doi.org/10.1016/j.bios.2015.01.027

Care D. 6. Glycemic targets: standards of medical care in diabetes-2019. Diabetes Care. 2019 ; 42(Supplement 1):S61- 70. https://doi.org/10.2337/dc19-S006 DOI: https://doi.org/10.2337/dc19-S006

Verma N, Usman K, Patel N, Jain A, Dhakre S, Swaroop A, Bagchi M, Kumar P, Preuss HG, Bagchi D. A multicenter clinical study to determine the efficacy of a novel fenugreek seed (Trigonella foenum-graecum) extract (Fenfuro™) in patients with type 2 diabetes. Food and Nutrition Research. 2016; 60(1):32382. https://doi.org/10.3402/fnr.v60.32382 DOI: https://doi.org/10.3402/fnr.v60.32382

Ranade M, Mudgalkar N. A simple dietary addition of fenugreek seed leads to the reduction in blood glucose levels: A parallel group, randomised single-blind trial. Ayu. 2017; 38(1-2):24. https://doi.org/10.4103/ayu.AYU_209_15 DOI: https://doi.org/10.4103/ayu.AYU_209_15

Vijaya B. Exploration and Docuhentation of Indigenous Hypoglycemic Substances of North Karnataka and Impact of Periwinkle Leaves (Catharanthus roseus) on Management of Diabetes Mellitus (Doctoral dissertation, University of Agricultural Sciences GKVK, Bangalore).

Satyanarayana K, Sravanthi K, Shaker IA, Ponnulakshmi R. Molecular approach to identify anti-diabetic potential of Azadirachta indica. Journal of Ayurveda and Integrative Medicine. 2015; 6(3):165. https://doi.org/10.4103/0975- 9476.157950 DOI: https://doi.org/10.4103/0975-9476.157950

Saeed F, Arshad MS, Nisa M, Nadeem MT, Arshad MU. Hypoglycemic and hypolipidemic effects of different parts and formulations of bitter gourd (Momordica charantia). Lipids in health and disease. 2017; 16(1):1-1. https://doi. org/10.1186/s12944-017-0602-7 DOI: https://doi.org/10.1186/s12944-017-0602-7

Efird JT, Choi YM, Davies SW, Mehra S, Anderson EJ, Katunga LA. Potential for improved glycemic control with dietary Momordica charantia in patients with insulin resistance and pre-diabetes. International Journal of Environmental Research and Public Health. 2014; 11(2):2328-45. https://doi.org/10.3390/ijerph110202328 DOI: https://doi.org/10.3390/ijerph110202328

Muralidharan L. Beneficial effects of Aegle marmelos leaves on blood glucose levels and body weight changes in alloxaninduced diabetic rats. J Med Plants Stud. 2014; 2(4):46-9.

Geberemeskel GA, Debebe YG, Nguse NA. Antidiabetic effect of fenugreek seed powder solution (Trigonella foenum- graecum L.) on hyperlipidemia in diabetic patients. Journal of Diabetes Research. 2019; 2019. https://doi. org/10.1155/2019/8507453 DOI: https://doi.org/10.1155/2019/8507453

Kooti W, Farokhipour M, Asadzadeh Z, Ashtary-Larky D, Asadi-Samani M. The role of medicinal plants in the treatment of diabetes: A systematic review. Electronic Physician. 2016; 8(1):1832. https://doi.org/10.19082/1832 DOI: https://doi.org/10.19082/1832

Modak M, Dixit P, Londhe J, Ghaskadbi S, Devasagayam TP. Indian herbs and herbal drugs used for the treatment of diabetes. Journal of Clinical Biochemistry and Nutrition. 2007; 40(3):163-73. https://doi.org/10.3164/jcbn.40.163 DOI: https://doi.org/10.3164/jcbn.40.163

Banerjee S, Bhattacharjee P, Kar A, Mukherjee PK. LC-MS/ MS analysis and network pharmacology of Trigonella foenum-graecum - A plant from Ayurveda against hyperlipidemia and hyperglycemia with combination synergy. Phytomedicine. 2019; 60:152944. https://doi.org/10.1016/j. phymed.2019.152944 DOI: https://doi.org/10.1016/j.phymed.2019.152944

Baquer NZ, Kumar P, Taha A, Kale RK, Cowsik SM, McLean P. Metabolic and molecular action of Trigonella foenum- graecum (fenugreek) and trace metals in experimental diabetic tissues. Journal of Biosciences. 2011; 36(2):383-96. https://doi.org/10.1007/s12038-011-9042-0 DOI: https://doi.org/10.1007/s12038-011-9042-0