Genotoxicity Assessment of Hydroalcoholic Extract of Bark of Terminalia arjuna (Combretaceae)

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Authors

  • Alex Thomas
     Department of Chemistry, School of Advanced Sciences, VIT, Vellore – 632014, Tamil Nadu ,IN
  • Ethiraj K. R.
     Department of Chemistry, School of Advanced Sciences, VIT, Vellore – 632014, Tamil Nadu ,IN

DOI:

https://doi.org/10.18311/jnr/2023/28309

Keywords:

Ames Test, Chromosomal Aberration Test, CHO Cell Lines, Hydroalcoholic Extract, Terminalia arjuna
Phytochemical

Abstract

The mutagenic potential of Terminalia arjuna hydroalcoholic bark extract was evaluated using Ames test with strains TA98, TA100, TA102, TA1535, and TA1537. The genotoxic potential was assessed by performing Chromosomal Aberration test with cell lines of CHO. In the assessment of mutagenic potential by the Ames test, hydroalcoholic extract of Terminalia arjuna induced a negative response and in Chromosomal Aberration test, it did not show any significant genotoxic activity in the CHO cell lines.

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Published

2023-06-13

How to Cite

Thomas, A., & K. R., E. (2023). Genotoxicity Assessment of Hydroalcoholic Extract of Bark of <i>Terminalia arjuna</i> (Combretaceae). Journal of Natural Remedies, 23(2), 403–413. https://doi.org/10.18311/jnr/2023/28309

Issue

Volume 23, Issue 2, April 2023

Section

Research Articles

License

Copyright (c) 2023 Alex Thomas, Ethiraj K.R

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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Europe PMC
Received 2021-07-26
Accepted 2023-05-02
Published 2023-06-13

 

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