Wheatgrass (Triticum aestivum) Extract Reduces Inflammatory TNF-Alpha Response in Experimentally Induced Gastric Ulceration in Rat Model

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Authors

  • Sainu Susan Oommen
     Department of Anatomy, Father Muller Medical College, Kankanady – 575001, Mangalore, Karnataka ,IN

DOI:

https://doi.org/10.18311/jnr/2024/30528

Keywords:

Gastric Ulcer, TNF-α, Triticum aestivum, Ulcer-Index, Wheat Grass Extract

Abstract

Background: The term ‘peptic ulcer’ refers to the ulcers that occur in either the stomach or the first part of the small intestine that leads out of the stomach, called the duodenum. Aim: The present study aims to examine the protective consequence of wheatgrass (Triticum aestivum) extract on ethanol-induced gastric ulceration in Albino Wistar rats. Methods: The extract of wheatgrass significantly reduced gastric ulceration in rats in comparison to the control ethanol group. Results: Consequently, a remarkable decrease in the inflammatory activity of the TNF-α was observed in ethanol-induced ulcerated rats receiving treatment with wheatgrass extract. The gastric volume and ulceration increased with oral administration of ethanol. A drastic decrease in the total acidity and ulcer index was observed in rats treated with wheatgrass extract. In the protective index percentage, a substantial increase was observed with doses of the wheatgrass extract. Conclusion: These results suggest the gastro-protective effect of wheatgrass extract.

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Published

2024-06-30

How to Cite

Oommen, S. S. (2024). Wheatgrass (<i>Triticum aestivum</i>) Extract Reduces Inflammatory TNF-Alpha Response in Experimentally Induced Gastric Ulceration in Rat Model. Journal of Natural Remedies, 24(6), 1341–1346. https://doi.org/10.18311/jnr/2024/30528

Issue

Volume 24, Issue 6, June 2024

Section

Short Communication

License

Copyright (c) 2024 Sainu Susan Oommen, Hilda Fernandes, Rajendra Holla

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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Europe PMC
Received 2022-06-22
Accepted 2024-02-21
Published 2024-06-30

 

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