Detection of Antibacterial Activity of Garlic Against Acinetobacter Species Isolated from Patients in Tertiary Care Hospital

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Authors

  • Sareena Rao
     Department of Microbiology, MGM Medical College and Hospital, Kamothe, Navi Mumbai – 410209, Maharashtra ,IN
  • Deepashri Naik
     Department of Microbiology, MGM Medical College and Hospital, Kamothe, Navi Mumbai – 410209, Maharashtra ,IN

DOI:

https://doi.org/10.18311/jnr/2023/31916

Keywords:

Acinetobacter species, Allium sativum (Garlic), Antibacterial Activity

Abstract

The aim of the present study evaluates the antibacterial activity of garlic extracts on isolates of Acinetobacter. A total of 100 strains were collected from various samples at MGM hospital in Kamothe, Navi Mumbai. The susceptibilities of isolates to different antibiotics were tested by using the Kirby Bauer agar disk diffusion method. Seventy-nine per cent of isolated strains showed resistance to at least 14 or more antibiotics and all strains are multidrug resistant. Antibacterial activity of different concentrations of Garlic Extract was measured by well diffusion and the disk diffusion method. Garlic extract was used in the range of 5% to 100%. The present study suggests that multidrug-resistant Acinetobacter bacteria with significant antibiotic resistance show significant susceptibility to modest amounts of garlic extracts.

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Published

2023-05-23

How to Cite

Rao, S., & Naik, D. (2023). Detection of Antibacterial Activity of Garlic Against Acinetobacter Species Isolated from Patients in Tertiary Care Hospital. Journal of Natural Remedies, 23(2), 671–675. https://doi.org/10.18311/jnr/2023/31916

Issue

Volume 23, Issue 2, April 2023

Section

Short Communication

License

Copyright (c) 2022 Sareena Rao, Deepashri Naik (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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Europe PMC
Received 2022-11-11
Accepted 2023-02-02
Published 2023-05-23

 

References

Ananthanarayan R. Ananthanarayan and Paniker’s textbook of microbiology. Orient Blackswan; 10th ed; 2017. p. 404-5.

Sastry AS, Bhat S. Essentials of medical microbiology. JP Medical Ltd; 3rd ed; 2021. p. 645-646.

Jung J, Park W. Acinetobacter species as model microorganisms in environmental microbiology: current state and perspectives. Applied Microbiology and Biotechnology. 2015; 99(6):2533-48. https://doi.org/10.1007/s00253-015-6439-y PMid:25693672 DOI: https://doi.org/10.1007/s00253-015-6439-y

Yadav S, Trivedi NA, Bhatt JD. Antimicrobial activity of fresh garlic juice: An in vitro study. Ayu. 2015; 36(2):203. https://doi.org/10.4103/0974-8520.175548 PMid:27011724 PMCid:PMC4784133 DOI: https://doi.org/10.4103/0974-8520.175548

Strika I, Bašić A, Halilović N. Antimicrobial effects of garlic (Allium sativum L.). Bulletin of the Chemists and Technologists of Bosnia and Herzegovina. 2017; 47(7): 17-20.

Bayan L, Koulivand PH, Gorji A. Garlic: A review of potential therapeutic effects. Avicenna J Phytomed. 2014; 4(1):1-14.

Calsamiglia S, Busquet M, Cardozo PW, Castillejos L, Ferret A. Invited review: Essential oils as modifiers of rumen microbial fermentation. Journal of Dairy Science. 2007; 90(6):2580-95. https://doi.org/10.3168/jds.2006-644 PMid:17517698 DOI: https://doi.org/10.3168/jds.2006-644

Sharma R, Otieno S, Otieno S. Kirby Bauer disc diffusion method for antibiotic susceptibility testing. Microbe Notes; 2022.

Vineetha N, Vignesh RA, Sridhar D. Preparation, standardization of antibiotic discs and study of resistance pattern for first-line antibiotics in isolates from clinical samples. International Journal of Applied Research. 2015; 1(11): 624-31.

Yadav M, Bohra R, Gupta N. In vitro determination of antibacterial effect of garlic (Allium sativum) on Staphylococcus aureus and E. coli. Int J Curr Microbiol Appl Sci. 2019; 8(09):498506. https://doi.org/10.20546/ijcmas.2019.809.060 DOI: https://doi.org/10.20546/ijcmas.2019.809.060

Das S, Basak S. Acinetobacter baumanii complex and its beta-lactamase production: Are we moving towards pre antibiotic era? Int J Health Sci Res. 2018; 8(3):60-69.

Musyoki V, Masika M, Mutai W, Gitau W, Kuria A, Muthini F. Antimicrobial susceptibility pattern of acinetobacter isolates from patients in Kenyatta National Hospital, Nairobi, Kenya. Pan African Medical Journal. 2019; 33. DOI: https://doi.org/10.11604/pamj.2019.33.146.17220

https://doi. org/10.11604/pamj.2019.33.146.17220 PMid:31558943 PMCid:PMC6754852

Cirkovic I, Jovalekic M, Jegorovic B. In vitro antibacterial activity of garlic and synergism between garlic and antibacterial drugs. Archives of Biological Sciences. 2012; 64(4):1369-75. https://doi.org/10.2298/ABS1204369C DOI: https://doi.org/10.2298/ABS1204369C

Jazani NH, Shahabi S, Ali AA, Zarrin S, Daie NA. In vitro antibacterial activity of garlic against isolates of Acinetobacter sp. Journal of Biological Sciences. 2007; 7(5):819-22. https://doi.org/10.3923/jbs.2007.819.822 DOI: https://doi.org/10.3923/jbs.2007.819.822

Ain Q, Naeem S, Naim A. Antibacterial activity of ethanolic plant extracts on multidrug-resistant Acinetobacter baumannii clinical isolates. Pakistan Journal of Botany. 2022; 54(5). https://doi.org/10.30848/PJB2022-5(35) DOI: https://doi.org/10.30848/PJB2022-5(35)