Conventional Remedy to Lou Gehrig’s Disease - Amyotrophic Lateral Sclerosis (ALS): A Rare Clinical Entity

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Authors

  • Department of Shalakyatantra, Dr. D. Y. Patil College of Ayurved and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pimpri, Pune – 411018, Maharashtra ,IN
  • Department of Shalakyatantra, Dr. D. Y. Patil College of Ayurved and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pimpri, Pune – 411018, Maharashtra ,IN
  • Department of Panchkarma, Dr. D. Y. Patil College of Ayurved and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pimpri, Pune – 411018, Maharashtra ,IN

DOI:

https://doi.org/10.18311/jnr/2023/34259

Keywords:

Amyotrophic Lateral Sclerosis, Jivha Pratisarana, Lou Gehrig’s Disease, Nasya

Abstract

Lou Gehrig’s disease, commonly known as amyotrophic lateral sclerosis, is an incredibly rare clinical condition that affects about 5 in 100,000 people annually in India, making it one of the rarest diseases in the entire world. With an average age of 55, this disease typically impacts people between the ages of 40 and 70. Males are more prone to develop the condition. Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder affecting primarily the motor system, but in which extramotor manifestations are increasingly recognized. The loss of upper and lower motor neurons in the motor cortex, the brain stem nuclei and the anterior horn of the spinal cord gives rise to progressive muscle weakness and wasting. Typically, patients report difficulties swallowing or a shift in voice pitch while speaking due to tongue involvement. Initial ALS symptoms can resemble those of other neuromuscular illnesses and are completely non-specific. In this case report, we described a 44-year-old gentleman who has been diagnosed with Amyotrophic Lateral Sclerosis in accordance to an MRI scan describing symptoms like unable to speak, reduced tongue movements, trouble swallowing, excessive salivation, swelling over the tongue and loss of tongue tone for the past three to four months. The present study discusses the clinical presentation, diagnosis, therapeutic regimen and prognosis. Both allopathic and ayurvedic oral medications with local therapeutic regimens like Jivha Pratisarana (Rubbing of dry powder on tongue) and Nasya (nasal drops of medicated oil) were employed in the patient which have satisfactory results enhancing for betterment of lifestyle.

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Published

2023-11-08

How to Cite

Gupta, D., Shiralkar, M., & Chaudhari, V. (2023). Conventional Remedy to Lou Gehrig’s Disease - Amyotrophic Lateral Sclerosis (ALS): A Rare Clinical Entity. Journal of Natural Remedies, 23(4), 1563–1570. https://doi.org/10.18311/jnr/2023/34259

Issue

Section

Case Report
Received 2023-06-30
Accepted 2023-09-08
Published 2023-11-08

 

References

Walker BR, Colledge NR, Ralston SH, Penman ID. Davidson’s principle and practice of medicine, Motor Neuron Disease, 22 edn; 2014. p. 1200b-1201b.

Ingre C, Roos PM, Peihl F, Kamel F, Fang F. Risk factors for amyotrophic lateral sclerosis. Clinical Epidemiology. 2015; 7:181-93. https://doi.org/10.2147/CLEP.S37505 DOI: https://doi.org/10.2147/CLEP.S37505

Belsh JM, Schiffman P. Amyotrophic lateral sclerosis: Diagnosis and management for the clinician. Armonk: N.Y. Futura; 1996. p. 286-90.

Anni D, Walling MD. Amyotrophic lateral sclerosis: Lou Gehrig’s disease. American Family Physician. 1999; 59(6):1489-96.

Masrori P, Van Damme P. Amyotrophic lateral sclerosis: A clinical review. European Journal of Neurology. 2020; 27(10):1918-29. https://doi.org/10.1111/ene.14393 DOI: https://doi.org/10.1111/ene.14393

Jaiswal MK. Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs. Medicinal Research Reviews. 2018; 39(2):733-48. https://doi.org/10.1002/med.21528 DOI: https://doi.org/10.1002/med.21528

Lohan, V. Trigeminal neuralgia- ayurveda approach: A case study. World Journal of Pharmaceutical Research. 2023; 12(4): 1346-55.

Agnivesha, elaborated by Charaka and Dridhabala commentary by Chakrapani, Charaka Samhita, Trimarmeeya siddhi adhyaya, by Vaidya Yadavji Trikamji Acharya and Narayana Ram Acharya. Varanasi: Chaukhamba Orientalia; 2008.

Acharya YT, SushrutaSamhita of Sushruta, ShariraSthana, Ch. 6., Ver. 79. 1st ed. Varanasi: Chowkhamba Publishing House (Reprint); 2017. p. 187.

Sultana, KJM, Rathi S. A case study on the Ayurvedic management of sixth (Abducens) nerve palsy. Journal of Ayurveda and Integrated Medical Sciences. 2023; 8(4). https://doi.org/10.21760/jaims.8.4.36

Surpam YA, Khiyani RM. Critical review and probable mode of action of agnitundi rasa - A herbomineral formulation. World Journal of Pharmaceutical Research. 2021; 10(9):625-37.

Sharma LK, Prasad GP, Maheswar T. A clinical study on Pakshaghata (Hemiplegia) with a combination therapy of ekanga veera ras, masha taila and shastikashali pinda sweda. Journal of Research in Ayurvedic Sciences. 2004; xxv(1-2):53-66.

Mohan M, Sawarkar P. Ayurvedic management of Gridhrasi with special respect to sciatica: A case report. Journal of Indian System of Medicine. 2019; 7:131-8. https://doi.org/10.4103/JISM.JISM_38_19 DOI: https://doi.org/10.4103/JISM.JISM_38_19

Sultana KJN. A case study on the Ayurvedic management of sixth (abducens) nerve palsy. Journal of Ayurveda and Integrated Medical Sciences. 2023; 8(4). https://doi.org/10.21760/jaims.8.4.36 DOI: https://doi.org/10.21760/jaims.8.4.36

Moger SN, Rajendra V. A clinical study to evaluate the efficacy of Ashtanga Ghrita in Dementia. Journal of Ayurveda and Integrated Medical Sciences. 2021; 6(5):33-7.

Zee-Ihn Lee, Dong-Hyun Cho, Won-Duck Choi, Dong-Hwi Park, Seung-Deuk Byun. Effect of Botulinum Toxin Type A on Morphology of Salivary Glands in Patients with Cerebral Palsy. Annals of Rehabilitation Medicine. 2011; 35:636-640. DOI: https://doi.org/10.5535/arm.2011.35.5.636

Luiz Roberto Lopes, Natha´lia da Silva Braga, Gustavo Carvalho de Oliveira, Joa˜ o de Souza Coelho Neto, Marcelo Amade Camargo, Nelson Adami Andreollo. Results of the surgical treatment of non-advanced megaesophagus using Heller–Pinotti’s surgery: Laparotomy vs. Laparoscopy. Clinics. 2011; 66(1):41-46. DOI: https://doi.org/10.1590/S1807-59322011000100008