Exploring the Therapeutic Potential of Caesalpinia bonducella for Male and Female Reproductive Health: A Comprehensive Review

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Authors

  • Ragunathan Muthuswamy
     Department of Pharmacognosy, Swamy Vivekanandha College of Pharmacy Tamiln Ndu, Dr. M. G. R. Medical University, Tiruchengodu, Namakkal – 637205, Tamil Nadu ,IN
  • Ranil Ramana Ragunathan
     Cantho University of Medicine and Pharmacy, 179 Nguyen Van Cu Street, An Khanh, Ninh Kieu, Can Tho ,VN
  • Senthil Rajan Dharmalingam
     Department of Pharmaceutics, Swamy Vivekananda College of Pharmacy, Elayampalayam, Namakkal – 637205, Tamil Nadu ,IN
  • Kumarappan Chidambaram
     Department of Pharmacology, College of Pharmacy, King Khalid University, Abha – 62529 ,SA
  • Manimekalai Pichaivel
     Department of Pharmacology, Swamy Vivekananda College of Pharmacy, Elayampalayam, Namakkal – 637205, Tamil Nadu ,IN
  • Sanghavi
     Department of Pharmacology, Swamy Vivekananda College of Pharmacy, Elayampalayam, Namakkal – 637205, Tamil Nadu ,IN

DOI:

https://doi.org/10.18311/jnr/2024/34981

Keywords:

Anti-progesterogenic, Anti-spermatogenic, Caesalpinia bonducella, Male Contraceptive, Neuroprotective, PCOS, Testosterone Booster

Abstract

This review explores the potential of Caesalpinia bonducella Linn., particularly its seeds, known as ‘bounducella’ or ‘little ball’, and its impact on diverse pharmacological activities. Its use in treating various illnesses, including male and female reproductive health, has been investigated. The data, gathered from reliable sources worldwide, transcend language barriers and align with Indian Ayurvedic and Siddha Pharmacopoeias. This article has compiled the pharmacognostic and phytochemical profiles of the seeds, emphasizing their influence on reproductive health, potentially aiding in PCOS management and addressing hyperandrogenism. Additionally, the seed extract of this plant has abortifacient and anti-fertility effects, suggesting that it is a potential alternative to Mifepristone. Nevertheless, further in vivo and in vitro research on seed constituents is essential for developing lead molecules for use in allopathic treatment.

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Published

2024-03-01

How to Cite

Muthuswamy, R., Ragunathan, R. R., Dharmalingam, S. R., Chidambaram, K., Pichaivel, M., & Sanghavi. (2024). Exploring the Therapeutic Potential of <i>Caesalpinia bonducella</i> for Male and Female Reproductive Health: A Comprehensive Review. Journal of Natural Remedies, 24(3), 431–439. https://doi.org/10.18311/jnr/2024/34981

Issue

Volume 24, Issue 3, March 2024

Section

Review Articles

License

Copyright (c) 2024 Ragunathan Muthuswamy , Ranil Ramana Ragunathan, Senthil Rajan Dharmalingam, Kumarappan Chidambaram, Manimekalai Pichaivel, Sanghavi (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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Received 2023-09-08
Accepted 2023-11-30
Published 2024-03-01

 

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