Anti-Dermatophytic Activity of Some Indian Medicinal Plants

J. Vaijayanthimala; N. Rajendra Prasad; C. Anandi; K. V. Pugalendi

doi:10.18311/jnr/2004/377

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Authors

J. Vaijayanthimala
,IN
N. Rajendra Prasad
,IN
C. Anandi
,IN
K. V. Pugalendi
,IN

DOI:

https://doi.org/10.18311/jnr/2004/377

Keywords:

Dermatophytosis, Trichophyton rubrum, Trichophyton mentagrophytes, Medicinal Plants.

Therapeutic Drug Monitoring

Abstract

Objective: Anti-dermatophytic activities of 23 South Indian medicinal plant materials have been studied using five isolates of Trichophyton rubrum and four isolates of Trichophyton mentagrophytes obtained from the patients of Raja Muthiah Medical College & Hospital, India and compared. Materials and methods: Water and ethanol extracts were prepared and their minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were determined. Results and conclusion: Ethanol extracts of plants exhibited more activity than water extracts. Among 23 plants garlic showed least MIC & MFC. In addition, ethanolic extracts of 11 plants showed less than 11.5 mg/ml MFC against T. rubrum and 9 plants showed less than 11.5 mg/ml MFC against T. mentagrophytes.