In vitro Antibacterial Activity of Manilkara hexandra (Sapotaceae) Seed Extracts and Violacein against Multidrug Resistant Streptococcus mutans

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Authors

  • Krishna Patel
     ,IN
  • Arwa Kaizer Ali
     ,IN
  • Nishith Nair
     ,IN
  • Vijay Kothari
     ,IN

DOI:

https://doi.org/10.18311/jnr/2015/466

Keywords:

Bactericidal, Biofilm, Microwave assisted extraction, Total activity
Therapeutic Drug Monitoring

Abstract

Extracts of the Pongamia pinnata, Manilkara hexandra, and Pyrus pyrifolia seeds prepared by microwave assisted extraction method, and the violet pigment- violacein extracted from Chromobacterium violaceoum were screened for their antibacterial activity against Streptococcus mutans.M. hexandra extracts were able to inhibit both the test strains of S. mutans used in this study with minimum inhibitory concentration (MIC) ranging from 600-800 µg/mL. These extracts exerted bactericidal action against S. mutans with minimum bactericidal concentration (MBC) of 600-900 µg/mL. Acetone extract of M. hexandra seeds registered highest average total activity of 231.20 mL/g. Extraction efficiency was found to have a moderately good correlation with antibacterial activity. Violacein exerted bactericidal action with MIC and MBC of less than 2 µg/mL against both the strains.

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Author Biography

Vijay Kothari

Assistant Professor

Institute of Science

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Published

2015-01-28

How to Cite

Patel, K., Ali, A. K., Nair, N., & Kothari, V. (2015). In vitro Antibacterial Activity of <i>Manilkara hexandra</i> (Sapotaceae) Seed Extracts and Violacein against Multidrug Resistant <i>Streptococcus mutans. Journal of Natural Remedies, 15(1), 1–11. https://doi.org/10.18311/jnr/2015/466

Issue

Volume 15, Issue 1, January 2015

Section

Articles
Crossref
Scopus
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Europe PMC
Received 2015-10-06
Accepted 2015-11-18
Published 2015-01-28

 

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