Screening of Pyrrolizidine Alkaloids in some Herbal Drugs
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Therapeutic Drug Monitoring
DOI:
https://doi.org/10.18311/jnr/2001/69Keywords:
Phyllanthus amarus, Pyrrolizidine Alkaloids, TLC, Polyherbal Formulations.Abstract
Objective: Detection of pyrrolizidine alkaloids (PA) in some polyherbal formulations. Materials and methods: Silica gel TLC with specific spray reagent for PA. Results: None of the herbal formulations tested were positive for PA. Phyllanthus amarus roots were found to contain PA. Conclusion: TLC method is recommended for routine detection of PA in plant drugs.Downloads
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