Steroids as a Boon in Oral Pemphigus Vulgaris: A Case Report and Treatment Overview

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Authors

  • Axita C. Dedhia
     Department of Oral Pathology, Government Dental College and Hospital, Mumbai, Maharashtra ,IN
  • Ramniwas M. Kumawat
     Department of Oral Pathology and Microbiology, Center for Dental Education and Research (AIIMS), New Delhi ,IN
  • Priyanka S. Kadoo
     Department of Oral Pathology and Microbiology, SDKS Dental College and Hospital, Nagpur, Maharashtra ,IN
  • Vishal D. Solanke
     Department of Oral Pathology and Microbiology, Dr. HSRSM's Dental College and Hospital, Hingoli, Maharashtra, ,IN
  • Ravi Tale
     Department of Oral Pathology and Microbiology, Saraswati-Dhanwantari Dental College and Hospital, Parbhani, Maharashtra ,IN
  • Neeta Bokade
     Ministry of Health ,BH

Keywords:

Corticosteroids, Mucous membrane, Oral ulcer, Pemphigus vulgaris
Oral and Maxillofacial Pathology

Abstract

Pemphigus vulgaris (PV) is an autoimmune blistering disease characterized by circulating pathogenic IgG autoantibodies against desmoglein 3 and desmoglein 1. Oral lesions readily rupture, new bullae developing as the older ones rupture and ulcerate. Oral lesions may precede cutaneous lesions in 53.52% cases. Prompt recognition and diagnosis is critical since it may prevent cutaneous involvement. Systemic steroids remain the gold standard treatment of PV. Their use has transformed what was almost invariably a fatal illness into one whose mortality is now below 10%. We report a case of patient with oral ulcers since 4 months, who is diagnosed with PV without cutaneous involvement.

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Published

2018-05-02

How to Cite

Dedhia, A. C., Kumawat, R. M., Kadoo, P. S., Solanke, V. D., Tale, R., & Bokade, N. (2018). Steroids as a Boon in Oral Pemphigus Vulgaris: A Case Report and Treatment Overview. Journal of Pierre Fauchard Academy (India Section), 31(1), 22–24. Retrieved from https://informaticsjournals.co.in/index.php/jpfa/article/view/21033

Issue

Volume 31, Issue 1, March 2017

Section

Original Articles

License

All the articles published in JPFA are distributed under a creative commons license. The journal allows the author(s) to hold the copyright of their work (all usages allowed except for commercial purpose).

 

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