Evaluation of Clinical Effectiveness of Bioactive - Glass and Platelet - Rich Fibrin in the Management of Intrabony Defects - A Comparative Study

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Authors

  • M. Prem Blaisie Rajula
     Senior Lecturer, SRM Kattankulathur Dental College & Hospital, Chennai ,IN
  • Malathi Subramanioum
     HOD & Professor, Tamil Nadu Government Dental College & Hospital, Chennai ,IN
  • Muthukumaraswamy
     Professor, Tamil Nadu Government Dental College & Hospital, Chennai ,IN
  • Arjun Singh
     Post Graduate Student, Tamil Nadu Government Dental College & Hospital, Chennai ,IN

DOI:

https://doi.org/10.18311/jpfa/2018/22130

Keywords:

Blood Platelets, Glass, Intrabony, Regeneration
Dentistry

Abstract

Background: Platelet-Rich Fibrin (PRF), the second-generation platelet concentrate has various fringe benefits over other platelet concentrates. Just finite number of research works have concentrated on the utilization of PRF in combination with various kinds of bone grafts in intra-bony defects. Objective: The primary intention of this study was to determine the clinical and radiographical efficacy of Bioactive-glass with and without autologous PRF in the management of three-wall vertical defects. Methods: Twenty intrabony defects were arbitrarily chosen and treated either with Bioactive Glass (BG) alone or in mix with PRF (PRF/BG). Clinical parameters were documented preoperatively (baseline) and at six months post-operatively. Radiographic analysis was performed at baseline, third and sixth-month intervals. Results: The study outcome demonstrated that both treatment approaches were effectual. Significant decrease in the mean probing depth and gain in clinical attachment was observed in BG+PRF and BG groups as compared to baseline but was statistically insignificant at 6 months. (p=0.475, p=0.245 respectively). Radiographically, reduction in defect depth was significantly greater in BG+PRF group than BG group (p=0.007) at 6 months. Conclusion: Within the limitation of the current study, it is proposed that both treatment modalities are effective in the management of 3-wall intra-bony defects. The outcomes additionally uncovered that incorporation of PRF with BG has more successful and promising results. Hence in future, clinical trials with bigger sample size may be employed to further explore the potential benefits of PRF as a sole grafting material.

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Published

2018-12-14

How to Cite

Rajula, M. P. B., Subramanioum, M., Muthukumaraswamy, ., & Singh, A. (2018). Evaluation of Clinical Effectiveness of Bioactive - Glass and Platelet - Rich Fibrin in the Management of Intrabony Defects - A Comparative Study. Journal of Pierre Fauchard Academy (India Section), 32(3-4), 39–47. https://doi.org/10.18311/jpfa/2018/22130

Issue

Volume 32, Issue(3-4), September - December 2018

Section

Original Articles

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All the articles published in JPFA are distributed under a creative commons license. The journal allows the author(s) to hold the copyright of their work (all usages allowed except for commercial purpose).

 

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