Heat Shock Proteins In Pathology: A Review

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Authors

  • Deepti Garg Jindal
     Department of Oral Pathology and Microbiology, Bhojia Dental College and Hospital, Bhud, Baddi, Distt Solan, HP ,IN
  • Varun Jindal
     Department of Conservative Dentistry & Endodontics, Bhojia Dental College and Hospital, Baddi, Himachal Pradesh ,IN
  • Sonia Joshi
     Department of Oral Pathology and Microbiology, Bhojia Dental College and Hospital, Bhud, Baddi, Distt Solan, HP ,IN
  • Ishita Bhojia
     Bhojia Dental College and Hospital, Bhud, Baddi, Distt Solan, HP ,IN
  • Arjun Chawdhry
     Bhojia Dental College and Hospital, Bhud, Baddi, Distt Solan, HP ,IN

Keywords:

Hsps, OLP, OSMF, Carcinogenesis
Oral Pathology

Abstract

Heat shock proteins of the 70 kDa family (HSPAs/HSP70s) are major molecular chaperones and cytokines of most cells and microbes, extracellular and interstitial fluids, blood, synovial fluids and secretory body fluids like saliva. The induction of human HSPAs plays an important role at cellular level under most stress conditions. HSPAs play a role in numerous physiological and pathological events, including modulation of cytokine release and immunity. Despite their advantageous effects maintaining health of several oral tissues, HSPAs are likely to play a role in the progression of pathological conditions like OLP, OSMF and Carcinogenesis. The review attempts to provide a critical overview of Hsps and their divergent roles in cellular processes particularly in the context of human health and disease.

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Published

2018-09-18

How to Cite

Jindal, D. G., Jindal, V., Joshi, S., Bhojia, I., & Chawdhry, A. (2018). Heat Shock Proteins In Pathology: A Review. Journal of Pierre Fauchard Academy (India Section), 30(3-4), 84–87. Retrieved from https://informaticsjournals.co.in/index.php/jpfa/article/view/22261

Issue

Volume 30, issue 3-4, September - December 2016

Section

Original Articles

License

All the articles published in JPFA are distributed under a creative commons license. The journal allows the author(s) to hold the copyright of their work (all usages allowed except for commercial purpose).

 

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