Study of Psychiatric Morbidity among Patients with Chronic Obstructive Pulmonary Disease in a Tertiary Health Care Institute
DOI:
https://doi.org/10.18311/mvpjms/2022/v9i1/282Keywords:
COPD, Major Depressive Disorder, Psychiatric Morbidity, Socio Demographic FactorsAbstract
Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a lung disease characterized by chronic obstruction of lung airflow that interferes with normal breathing and is not fully reversible. COPD is a progressive airway disease associated with psychological distress Screening the psychiatric disorders in COPD patients will be helpful in better management of the disease by assuring compliance as well as will help to improve quality of life of these patients leading to overall improvement in patients’ health, by helping in starting early psychiatry management whenever necessary. Methods: A single-center, cross-sectional, observational study performed at a tertiary care hospital between august 2016 and June 2018 to study psychiatric morbidity among patients with chronic obstructive pulmonary disease in a tertiary health care institute. A total of 68 clinically stable patients with COPD were screened for psychiatric morbidity by using Mini International Neuropsychiatric Interview (MINI) version 6.0.0. The clinical diagnosis was confirmed using DSM-5 and by qualified psychiatrist of the Department of Psychiatry. Result: Generalized anxiety disorder, Major depressive disorder, major depressive disorder with Anxiety, Panic attack, Phobia and Substance Abuse Disorder was present in 8.8%, 13.2%, 5.9%, 7.4%, 1.5% and 7.4% of study population respectively. Conclusions: We found that patients with COPD had high prevalence of depressive and anxious symptoms. Therefore, screening and treatment of these psychiatric comorbidities in patients with COPD may lead to significant improvements in patients’ quality of life.Downloads
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Mather CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med., 2006; 3(11):e442. https://doi.org/10.1371/journal.pmed. 0030442. PMid:17132052 PMCid:PMC1664601.
Mannino DM, Higuchi K, Yu TC, Zhou H, Li Y, Tian H, et al. Economic burden of chronic obstructive pulmonary disease by presence of comorbidities. Chest., 2015; 147:1199-1201. https://doi.org/10.1378/chest.15-0380. PMid:25940241.
Jindal SK. Indian Study on Epidemiology of Asthma, Respiratory Symptoms and Chronic Bronchitis (INSEARCH): A Multi Centre Study (2006-2009) - Final Report. New Delhi: Indian Council of Medical Research; 2010.
Kalucka S. The occurrence of Chronic Obstructive Pulmonary Disease (COPD) in cigarette smoking families. Przeg lLek., 2006; 63(10):848-857.
Pommer AM, Pouwer F, Denollet J, Pop VJM. Managing co-morbid depression and anxiety in primary care patients with asthma and/or chronic obstructive pulmonary disease: Study protocol for a randomized controlled trial. Trials., 2012; 13:6-13. https://doi.org/10.1186/1745-621513-6. PMid:22236488 PMCid:PMC3269377.
Ferrer M, Alonso J, Morera J, et al. Chronic obstructive pulmonary disease stage and health-related quality of life. Ann Intern Med., 1997; 127(12):1072-1079. https://doi.org/10.7326/0003-4819-127-12-19971215000003. PMid:9412309.
Wijnhoven HA, Kriegsman DM, Hesselink AE, Pennix BW, de Haan M. Determinants of different dimensions of disease severity in asthma and COPD. Chest., 2001; 119(4):1034-1042. https://doi.org/10.1378/chest.119.4.10 34. PMid:11296166.
Parekh PI, Blumenthal JA, Babyak MA, et al. Psychiatric disorder and quality of life in patients awaiting lung transplantation. Chest., 2003; 124(5):1682-1688. https:// doi.org/10.1378/chest.124.5.1682. PMid:14605035.
Van Manen JG, Bindels P, Dekker F, Jzermans CJI, van der Zee JS, Schade E. Risk of depression in patients with chronic obstructive pulmonary disease and its determinants.Thorax., 2002; 57(5):412-416. https://doi.org/10.1136/ thorax.57.5.412. PMid:11978917 PMCid:PMC1746339.
Hill K, Geist R, Goldstein RS, Lacasse Y. Anxiety and depression in end-stage COPD. Eur Respir J., 2008; 31(3):667677. https://doi.org/10.1183/09031936.00125707. PMid: 18310400.
Cooper CB. The connection between chronic obstructive pulmonary disease symptoms and hyperinflation and its impact on exercise and function. Am J Med., 2006; 119(10 Suppl 1):21-31. https://doi.org/10.1016/j.amjmed.2006.08.004. PMid:16996896.
Al-shair K, Dockry R, Mallia-Milanes B, et al. Depression and its relationship with poor exercise capacity, BODE index and muscle wasting in COPD. Respir Med., 2009; 103(10):1572-1579. https://doi.org/10.1016/j.rmed.2008.11.021. PMid:19560330.
Liao WC, Lin CL, Chang SN, Tu CY, Kao CH. The association between chronic obstructive pulmonary disease and dementia: A population-based retrospective cohort study. Eur J Neurol. 2015; 22:334-340. https://doi.org/10.1111/ene.12573, https://doi.org/10.1111/ene.12677, https://doi.org/10.1111/ene.12676.
Macnee W, Rabinovich RA, Choudhury G. Ageing and the border between health and disease. Eur Respir J., 2014; 4:1332-1352. https://doi.org/10.1183/09031936.00134014.PMid:25323246.
Mehta JR, Ratnani IJ, Dave JD, Panchal BN, Patel AK, Vala AU. Association of psychiatric co-morbidities and quality of life with severity of chronic obstructive pulmonary disease. East Asian Arch Psychiatry, 2014; 24:148-155.
Global Initiative for Chronic Obstructive Lung Disease.Accessed 5 Nov 2018. http://www.goldcopd.org.
Neufeld KJ, Peters DH, Rani M, Bonu S, Brooner RK. Regular use of alcohol and tobacco in India and its association with age, gender, and poverty. Drug Alcohol Depend, 2005; 77:283-291. https://doi.org/10.1016/j.drugalcdep.2004.08.022. PMid:15734228.
Jindal SK, Aggarwal AN, Gupta D. A review of population studies from India to estimate national burden of chronic obstructive pulmonary disease and its association with smoking. Indian J Chest Dis Allied Sci., 2001; 43:139-147.
Gania AM, Nabij J, Malik JA, Khan AW. Psychiatric co morbidities in patients of COPD and bronchial asthma attending OPD of tertiary care hospital. J Evolution Med Dent Sci., 2016; 5:920-924. https://doi.org/10.14260/ jemds/2016/214.
Light RW, Merrill EJ, Despars JA, Gordon GH, Mutalipassi LR. Prevalence of depression and anxiety in patients with COPD. Relationship to functional capacity. Chest., 1985; 87:35-38. https://doi.org/10.1378/chest.87.1.35.PMid:3965263.
Dowson C, Laing R, Barraclough R, Town I, Mulder R, Norris K, et al. The use of the Hospital Anxiety and Depression Scale (HADS) in patients with chronic obstructive pulmonary disease: A pilot study. N Z Med J., 2001; 114:447-449.
Stage KB, Middelboe T, Pisinger C. Measurement of depression in patients with Chronic Obstructive
Pulmonary Disease (COPD). Nord J Psychiatry, 2003; 57:297-301. https://doi.org/10.1080/08039480310002147.PMid:12888404.
Mikkelsen RL, Middelboe T, Pisinger C, Stage KB. Anxiety and depression in patients with Chronic
Obstructive Pulmonary Disease (COPD). A review. Nord J Psychiatry., 2004; 58:65-70. https://doi.
org/10.1080/08039480310000824. PMid:14985157.
Karajgi B, Rifkin A, Doddi S, Kolli R. The prevalence of anxiety disorders in patients with chronic obstructive pulmonary disease. Am J Psychiatry., 1990; 147:200-201. https://doi.org/10.1176/ajp.147.2.200. PMid:2301659.
Willgoss TG, Yohannes AM. Anxiety disorders in patients with COPD: A systematic review. Respir Care, 2013; 58:858-866. https://doi.org/10.4187/respcare.02774. PMid: 24064635.