Modulatory effect of vitamin E and C on SO^ induced hematological alterations in albino rats

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Authors

  • Asha Agarwal
     ,IN
  • Preeti Kumari
     ,IN
  • Madhuri yadav
     ,IN

DOI:

https://doi.org/10.18311/jeoh/2010/18247

Keywords:

SO gas. Hematological alterations. Albino rats, Vitamin E and C.

Abstract

The present study aimed to investigate the alterations in selected hematological parameters (total erythrocyte count, total leucocyte count, hemoglobin concentration, packed cell volume, erythrocyte sedimentation rate and red cell indices(MC V, MCH, MCHC) of wistar albino rats after short term (80 ppm, 1 h/ d for 28 days) exposure to SO ^ gas and protective effect of vitamin E (2.5mg/rat) andC (5mg/rat) individually and In combination. The results of the present study imply that hematological parameters altered after SO^ gas inhalation and lead to reduction in TEC, Hb.Conc, PCVand red cell indices, while elevation in TLC and ESR. However, SO^ induced hematological alterations modulated after supplementation of vitamin E and C individually and in combination due to antioxidant defense mechanism against toxic action of SO^ inhalation. The findings of the present study exhibit that the supplementation of vitamin E and C in combination have more potential to mitigate SO^ induced hematological alterations in albino rats than the supplementation of vitamin E and C individually.

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Author Biographies

Asha Agarwal

Department of Zoology, School of Life Sciences,
Dr. B.R.Ambedkar University, Khandari Campus, Agra-282002, India

Preeti Kumari

Department of Zoology, School of Life Sciences,
Dr. B.R.Ambedkar University, Khandari Campus, Agra-282002, India

Madhuri yadav

Department of Zoology, School of Life Sciences,
Dr. B.R.Ambedkar University, Khandari Campus, Agra-282002, India

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Published

2017-11-30

How to Cite

Agarwal, A., Kumari, P., & yadav, M. (2017). Modulatory effect of vitamin E and C on SO^ induced hematological alterations in albino rats. Journal of Ecophysiology and Occupational Health, 10(1-2), 5–8. https://doi.org/10.18311/jeoh/2010/18247

Issue

Volume 10, Issue 1-2, June 2010

Section

Articles
Crossref
Scopus
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Europe PMC
Received 2017-11-27
Accepted 2017-11-27
Published 2017-11-30

 

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