Clinical Spectrum and Epidemiology of Renal Diseases: Insights from Renal Biopsy: A Single Hospital Study
Authors
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Chandan Institute of Renal Sciences and Kidney Transplant, Chandan Hospital, Lucknow – 226010, Uttar Pradesh ,IN
Sant Kumar Pandey -
Chandan Institute of Renal Sciences and Kidney Transplant, Chandan Hospital, Lucknow – 226010, Uttar Pradesh ,INDhairya Prakash Prajapati
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Department of Medical Gastroenterology, King George’s Medical University, Lucknow – 226003, Uttar Pradesh ,INAmar Deep
DOI:
https://doi.org/10.18311/jeoh/2024/42116Keywords:
C3 Glomerulopathy, Crescentic Glomerulo Nephritis (GN), FSGS (Focal and Segmental Glomerulonephritis), IgA N (IgA Nephropathy), MCD (Minimal Change Disease), MN (Membranous Nephropathy), MPGN (Membranoproliferative Glomerulonephritis)Abstract
Introduction: Diagnosis of renal diseases through renal biopsy exhibits variability influenced by factors such as geographical location, ethnicity, age, gender and observer subjectivity. Aims: This study aimed to ascertain the frequency and distribution of various renal diseases diagnosed via renal biopsy at a tertiary care hospital in Lucknow, India. Materials and Methods: The study enrolled 187 patients who underwent renal biopsy between January 2020 and January 2023. Biopsies were conducted using percutaneous ultrasound-guided core needle biopsy, yielding two renal biopsy cores per patient. Results: The mean age of the patients was 35.7±16.8 years with a male predominance of 2.46:1. Primary glomerular diseases constituted 61.5% of cases, with IgA nephropathy as the most prevalent (21.4%), followed by focal and segmental glomerulonephritis (13.9%). Secondary glomerular diseases comprised 12.3% of cases with diabetic nephropathy being the most frequent (4.8%). Conclusion: The findings underscore the regional variability in renal disease patterns and highlight the crucial role of renal biopsy in accurate diagnosis and treatment decision-making. Further research is warranted to validate these observations and establish a national renal biopsy registry in India.
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Copyright (c) 2024 Sant Kumar Pandey, Dhairya Prakash Prajapati, Amar Deep
This work is licensed under a Creative Commons Attribution 4.0 International License.
Accepted 2024-04-08
Published 2024-05-16
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