Unlocking the Triad of Health: Investigating High Blood Pressure, Obesity and their Impact on PCOS in Women
DOI:
https://doi.org/10.18311/jeoh/2024/44378Keywords:
Hypertension, Lifestyle Disorders, Obesity, PCOS, Reproductive HealthAbstract
Polycystic Ovarian Syndrome or PCOS, is a common endocrine illness that affects 3.7% to 22.5% of fertile Indian women. It is characterised by abnormalities related to reproduction, metabolism, and hormones. This six-month prospective cohort study at Chalapathi Institute of Pharmaceutical Sciences examines the relationship between PCOS, obesity and high blood pressure. With 118 cases of PCOS detected among the 1246 participants who completed the comprehensive questionnaire, the study finds a substantial correlation between PCOS, obesity (p = 0.00061) and hypertension (p = 0.00061). Findings show that PCOS is more common in college students, underscoring the importance of lifestyle choices like nutrition, exercise and stress reduction. Additionally, the study finds that academics are more likely than IT workers or stay-at-home moms to have PCOS, which is associated with greater rates of obesity and hypertension. The results highlight the need for focused interventions, such as lifestyle changes and educational initiatives to reduce PCOS risk factors and enhance health outcomes. This study expands our understanding of PCOS and highlights the value of early detection and individualised treatment plans.
Downloads
Metrics
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Madala Teja Kalyani, Ravuri Neha Sree, Isireddy Nymisha Reddy, Mekala Rikitha, Sri Harshitha Komatineni, Jai Divya Tella, Siva Bharath Gavini, Ramarao Nadendla
This work is licensed under a Creative Commons Attribution 4.0 International License.
Accepted 2024-07-18
Published 2024-08-29
References
Patel S. Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy. J Steroid Biochem Mol Biol. 2018; 182:27-36. https://doi.org/10.1016/j.jsbmb.2018.04.008 PMid:29678491.
Anderson AD, Solorzano CM, McCartney CR. Childhood obesity and its impact on the development of adolescent PCOS. Semin Reprod Med. 2014; 32(3):202-13. https:// doi.org/10.1055/s-0034-1371092 PMid:24715515 PMCid: PMC4103796.
Perusquía M, Herrera N, Jasso-Kamel J, González L, Alejandre N. Hyperandrogenism protects against high blood pressure by nongenomic mechanisms and obesity causes hypertension in females with polycystic ovary syndrome. Endocr Res. 2023; 48(4):101-11. https://doi.org/10.1080/07435800.2023.2249087 PMid:37598377.
Bednarska S, Siejka A. The pathogenesis and treatment of polycystic ovary syndrome: What’s new? Adv Clin Exp Med. 2017; 26(2):359-67. https://doi.org/10.17219/acem/59380 PMid:28791858.
Osibogun O, Ogunmoroti O, Michos ED. Polycystic ovary syndrome and cardiometabolic risk: Opportunities for cardiovascular disease prevention. Trends Cardiovasc Med. 2020; 30(7):399-404. https://doi.org/10.1016/j.tcm.2019.08.010 PMid:31519403.
Aggarwal S, Pandey K. Early identification of PCOS with commonly known diseases: Obesity, diabetes, high blood pressure and heart disease using machine learning techniques. Expert Syst Appl. 2023; 217:119532. https://doi.org/10.1016/j.eswa.2023.119532
Mirza FG, Tahlak MA, Rjeili RB, Hazari K, Ennab F et. al. Polycystic ovarian syndrome (PCOS): Does the challenge end at conception? Int J Environ Res Public Health. 2022; 19(22):14914. https://doi.org/10.3390/ijerph192214914 PMid:36429632 PMCid: PMC9690374.
Gomez JMD, Van Hise K, Stachenfeld N, Chan JL, Merz NB, Shufelt C. Subclinical cardiovascular disease and polycystic ovary syndrome. Fertil Steril. 2022; 117(5):912-23. https:// doi.org/10.1016/j.fertnstert.2022.02.028 PMid:35512975 PMCid:PMC10322116.
Amiri M, Ramezani Tehrani F, Behboudi-Gandevani S, Bidhendi-Yarandi R, Carmina E. Risk of hypertension in women with polycystic ovary syndrome: A systematic review, meta-analysis and meta-regression. Reprod Biol Endocrinol. 2020; 18(1):23. https://doi.org/10.1186/s12958020-00576-1 PMid:32183820 PMCid:PMC7076940.
Gambineri A, Pelusi C, Vicennati V, Pagotto U, Pasquali R. Obesity and the polycystic ovary syndrome. Int J Obes. 2002; 26(7):883-96. https://doi.org/10.1038/sj.ijo.0801994 PMid:12080440.
Yildiz BO, Bozdag G, Yapici Z, Esinler I, Yarali H. Prevalence, phenotype and cardiometabolic risk of polycystic ovary syndrome under different diagnostic criteria. Hum Reprod. 2012; 27(10):3067-73. https://doi.org/10.1093/humrep/ des232 PMid:22777527.
Teede HJ, Misso ML, Costello MF, Dokras A, Laven J et. al. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Hum Reprod. 2018; 33(9):1602-18.
Bozdag G, Mumusoglu S, Zengin D, Karabulut E, Yildiz BO. The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod. 2016; 31(12):2841-55. https://doi.org/10.1093/humrep/dew218 PMid:27664216.
Bozdag G, Mumusoglu S, Zengin D, Karabulut E, Yildiz BO. The prevalence and phenotypic features of polycystic ovary syndrome: A systematic review and meta-analysis. Hum Reprod. 2016; 31(12):2841-55. https://doi.org/10.1093/humrep/dew218 PMid:27664216.