Solanum nigrum Leaves Improve the Oxidative Status of Liver Tissue In vitro
Authors
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Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore-641 043 ,IN
P. R. Padma -
Department of Biochemistry, Kongunadu Arts and Science College, Coimbatore-641 029 ,INK. Kalaivani
Abstract
All biological systems exist in a constant rage of redox reactions, which are a normal component of the metabolism. The oxidation- reduction status of a cell or tissue is maintained in a balanced state by various components in the cells. When this balance is tipped in favour of the oxidation reactions, a condition called oxidative stress ensues. Severe oxidative stress can result in several pathological conditions like diabetes, hypertension, cardiovascular disorders, neurological disorders and cancer. All aerobic organisms are equipped with an effective antioxidant defence system, which can efficiently counteract the oxidative stress.Downloads
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References
Carlsen, M.H., Halvorsen, B.L., Holte, K., Bí¸hn, S.K., Dragland, S., Sampson, L., Willey, C., Senoo, H., Umezono, Y., Sanada, C., Barikmo, I., Berhe, N., Willett, W.C., Phillips, K.M., Jacobs Jr, D.R. and Blomhoff, R. The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide. Nutr. J., 2010, Published online, doi: 10.1186/1475-2891-9-3.
Ravipati, A.S., Zhang, L., Koyyalamudi, S.R., Jeong, S.C., Reddy, N., Bartlett, J., Smith, P.T., Shanmugam, K., Münch, G., Wu, M.J., Satyanarayanan, M. and Vysetti, B. Antioxidant and anti-inflammatory activities of selected Chinese medicinal plants and their relation with antioxidant content, BMC Complement. Altern. Med., 12, 2012, Published online, doi: 10.1186/1472-6882-12-173.
Jimenez-Del-Rio, M. and Velez-Pardo, C. The Bad, the Good and the Ugly about Oxidative stress. Oxid. Med. Cell Longev., Published online, doi: 10.1155/2012/163913. 2012.
Slavin, J.L. and Lloyd, B. Health benefits of fruits and vegetables, Adv. Nutr., 2012, 3, 506-516.
Fillion, L. and Henry, C.J. Nutrient losses and gains during frying: a review. Int. J. Fd. Sci. Nutr., 1998, 49, 157-168.
Xianquan, S., Shi, J., Kakuda, Y. and Yueming, J. Stability of lycopene during food processing and storage. J. Med. Fd., 2005, 8, 413-422.
Tang, X., Wu, Q., Le, G. and Shi, Y. Effects of heat treatment on structural modification and in vivo antioxidant capacity of soy protein. Nutr., 2012, 28, 1180-1185.
Li, L., Li, X., Wang, AL., Jiang, Y. and Ban, Z. Effect of heat treatment on physiochemical, colour, antioxidant and microstructural characteristics of apples during storage. Int. J. Fd. Sci. Technol., 2013, 48, 727-734.
Tandon, S.L. and Rao, G.R. Solanum nigrum L in Evolutionary Studies in World Crops (Diversity and change in the Indian subcontinent). J. Hutchinson (ed.), 1974, 109-117.
Rao, G.R., Khan, R. and Khan, A.H. Cytomorphology and nature of sterility barriers of interspecific hybrids of some species of Solanum nigrum complex. Ind. J. Genet. Plant Breed., 1977, 37, 54-61.
Reemakumari, M. A taxonomic revision of the Indian Solanaceae, A thesis submitted to Bharathiar University, Coimbatore, India, for the degree of Doctor of Philosophy (Ph.D.) in Botany, Botanical Survey of India, Southern Circle, Coimbatore, Tamil Nadu, India. 2006.
Zhao, X., Song, J-L., Kil, J-H. and Park, K-Y. Bamboo salt attenuates CCl4-induced hepatic damage in Sprague-Dawley rats. Nutr. Res. Pract., 2013, 7, 273-280.
Das, K., Samanta, L. and Chainy, G.B.N. A modified spectrophotometric assay of superoxide dismutase using nitrite formation of superioxide radicals. Ind. J Biochem. Biophys., 2000, 37, 201-204.
Sinha, A.K. Colorimetric assay of catalase. Anal. Biochem., 1972, 47, 389-394.
Rotruck, J.T., Pope, A.L., Ganther, H.E. and Swanson, A.B., Hafeman, D.G. and Hoekstra, W.G. Selenium: Biochemical role as component of glutathione peroxidase. Sci., 1973,179, 588-590.
Habig, W.H., Pabst, M.J. and Jakoby, W.B. Glutathione S-transferase: The first enzymatic step in mercapturic acid formation. J. Biol. Chem., 1974, 249, 7130-7139.
David, M. and Richard, J.S. In: Methods of Enzymatic Analysis, Bergmeyer, J. and Grab, M. (Eds), Verlag Chemie Wenhein Deer Field, Beach Floride, 1983, 358.
Roe, J.H. and Keuther, C.A. The determination of ascorbic acid in whole blood and urine through 2,4-dinitrophenyl hydrazine derivative of dehydroascorbic acid. J.Biol. Chem., 1943,147, 399-407.
Rosenberg, H.R. Chemistry and Physiology of the Vitamins. Interscience Publisher, New York, 1992, 425-453.
Bayfield, R.F. and Cole, E.F. Colorimetric estimation of vitamin A with trichloroacetic acid. Meth. Enzymol., 1980, 67, 189-195.
Moron, M.S., Depierre, J.W. and Mannervik, B. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochem. Biophys. Acta., 1979, 582, 67-78.
Niehaus, W.G. and Samuelsson, B. Formation of malondialdehyde from phospholipids arachidonate during microsomal lipid peroxidation. Eur. J. Biochem., 1968, 6, 126-130.
Sim, C. and Denlinger, D.L. Catalase and superoxide dismutase-2 enhance survival and protect ovaries during overwintering diapause in the mosquito Culex pipiens. J. Insect Physiol., 2011, 57, 628-634.
Dragoni, S., Franco, G., Regoli, M., Bracciali, M., Morandi, V., Sparagli, G., Bertelli, E. and Valoti, M. Gold nanoparticles uptake and cytotoxicity assessed on rat liver precision-cut slices. Toxicol. Sci., 2012,128, 186-197.
Van Midwoud, P.M., Merema, M.T., Verweij, N., Groothuis, G.M.M. and Verpoorte, E. Hydrogel embedding of precision-cut liver slices in a microfluidic device improves drug metabolic activity. Biotechnol. Bioengg., 2011a, 108, 1404-1412.
Van Midwoud, P.M., Janssen, J., Merema, M.T., de Graaf, I.A.M., Groothuis, G.M.M. and Verpoorte, E. On-line HPLC analysis system for metabolism and inhibition studies in precision-cut liver slices. Anal. Chem., 2011b, 83, 84-91.
Rijk, J.C.W., Boveea, T.F.H., Peijnenburga, A.A.C.M., Groota, M.J., Rietjens, I.M.C.M. and Nielena, M.W.F. Bovine liver slices: A multifunctional in vitro model to study the prohormone dehydroepiandrosterone (DHEA). Toxicol. In Vitro, 2012, 26, 1014-1024.
Rajopadhye, A.A. and Upadhye, A.S. In vitro antioxidant and hepatoprotective effect of the whole plant of Glossocardia bosvallea (L.f.) D.C. against CCl4-induced oxidative stress in liver slice culture model. J. Herbs, Spices Med. Plants, 2012,18, 274-286.
Rop, O., Reznicek, V., Valsikova, M., Jurikova, T., Mlcek, J. and Kramarova, D. Antioxidant properties of European cranberrybush fruit (Viburnum opulus var. edule). Molecules, 2010, 15, 4467-4477.
Sreelatha, S. and Padma, P.R. Protective mechanisms of Moringa oleifera against CCl4-induced oxidative stress in precision-cut liver slices. Forsch. Komplementmed., 2010, 17, 189-194.
Palaniswamy, R. and Padma, P.R. Antioxidant activity of Majorana hortensis leaves subjected to oxidative stress in an in vitro system. Int. Res. J. Pharm., 2011a , 2, 153-157.
Radha, P. and Padma, P.R. Effect of Bacopa monnieri leaf extract on the antioxidant profile of goat liver slices subjected to oxidative stress, In: Proceedings of the National Conference on ‘Oxidative Stress and its Complications in Human Health', ISBN No.978–93–80697–53–6, Excel India Publishers, New Delhi, 2011, 195–200.
Nirmaladevi, R. and Padma, P.R. Free radical scavenging activity of Rhinacanthus nasutus leaves against oxidative damage induced under in vitro conditions. Adv. Pl. Sci., 2011, 24, 9-12.
Sumathi, S., Sowmini, C.M., Dharani, B., Sivaprabha, J. and Padma, P.R. Antioxidant status of goat liver slices treated with methanolic leaf extract of Nyctanthes arbor-tristis exposed to oxidative stress. Int. J. Pharm. Biol. Sci., 2011, 2, 376-382.
Balasubramanian, K. and Padma, P.R. Protection of precision-cut goat liver slices by Zea mays leaf extracts from hydrogen peroxide induced oxidative stress in vitro. Int. J. Pharm. Bio Sci., 2012, 3, 201-210.
Sivaprabha, J., Dharani, B., Padma, P.R. and Sumathi, S. In vitro prevention of oxidative damage by Curcuma amada in goat liver slices exposed to oxidative stress. J. Pharm. Res., 2012, 5, 1108-1110.
Yamuna, S.T. and Padma, P.R. Antioxidant potential of the flowers of Caesalpinia pulcherrima, Swartz in an in vitro system subjected to oxidative stress. J. Pharm. Res., 2013, 7, 661-665.
Mishra, S., Jha, A.B. and Dubey, R.S. Arsenite treatment induces oxidative stress, upregulates antioxidant system, and causes phytochlatin synthesis in rice seedlings. Protoplasma, 2011, 248, 565-577.
Cenini, A., G., Sultana, R.A., Memo, M. and Butterfield, A.D. Elevated levels of pro-apoptotic p53 and its oxidative modification by the lipid peroxidation product, HNE, in brain from subjects with amnestic mild cognitive impairment and Alzheimer's disease. J. Cell. Mol. Med., 2008, 12, 987-994.
Saumya, S.M. and Basha, M. Antioxidant effect of Lagerstroemia speciosa Pers (Banana) leaf extract in streptozotocin-induced diabetic mice. Ind. J. Exptl. Biol., 2011, 49, 125-131.
Das, L. and Vinayak, M. Anti-carcinogenic action of curcumin by activation of antioxidant defence system and inhibition of NF-íªB signalling in lymphoma-bearing mice. Biosci. Rep., 2012, 22, 161-170.
Palaniswamy, R. and Padma, P.R. Effect of Majorana hortensis leaves against lipid peroxidation. Asian J. Bio Sci., 2011b, 6, 87-89.
Oyedemi, S.O., Bradley, G. and Afolayan, A.J. In vitro and-vivo antioxidant activities of aqueous extract of Strychnos henningsii Gilg., Afr. J. Pharm. Pharmacol., 2010, 4, 70-78.
Afolayan, A.J. and Sumonu, T.O. Artemisia afra Jacq. ameliorates oxidative stress in the pancreas of streptozotocin-induced diabetic Wistar rats. Biosci. Biotechnol. Biochem., 2011, 75, 2083-2086.
