In Vitro Free Radical Scavenging Potential of Tabebuia pallida Leaf Extracts

Jump To References Section

Authors

  • Priyanka J.
     Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore – 641 043 ,IN
  • Suganya I.
     Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore – 641 043 ,IN
  • Nirmaladevi R.
     Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore – 641 043 ,IN

DOI:

https://doi.org/10.21048/IJND.2021.58.S3.28410

Keywords:

Phytochemicals, Tabebuia pallida, Free Radicals, Antioxidants, DPPH.

Abstract

Plants are the reservoir of various phytochemicals that gives more health benefits to the human body. They are widely used by our ancestors in traditional folk medicine. The major advantage of these phytochemicals is that they can be used to cure various diseases with little or no side effects. Free radicals play a major role in various disease conditions by causing damage to the cells. Antioxidants contribute an extensive part in defending the cells against damage and reduce the deleterious consequence of the free radicals mediated increased oxidant production. Plants contain a number of enzymic and non-enzymic antioxidants which render a better effect against these ailments. The main objective of the present study is to nalyse the antioxidant potential of various solvent extracts of Tabebuia pallida leaf. Free radical scavenging assays like, “DPPH, ABTS, hydroxyl radical, reducing power and nitric oxide assays’’, for the various solvents ``methanol, ethyl acetate, benzene, ethanol, chloroform, petroleum ether, acetone and water” of the leaf extracts of Tabebuia pallida were performed. All the extracts tested exhibit a remarkable radical scavenging effect as the concentration increases. So these antioxidant compounds from plant origin can be used as an alternative for the synthetic antioxidants that are available in the market.

Downloads

Download data is not yet available.

Downloads

Published

2022-02-01

How to Cite

J., P., I., S., & R., N. (2022). <i>In Vitro</i> Free Radical Scavenging Potential of <i>Tabebuia pallida</i> Leaf Extracts. The Indian Journal of Nutrition and Dietetics, 58(3), 10–19. https://doi.org/10.21048/IJND.2021.58.S3.28410

Issue

Volume 58, Supplement III, January-March 2021

Section

Articles

License

All the articles published in IJND are distributed under a creative commons license. The journal allows the author(s) to hold the copyright of their work (all usages allowed except for commercial purpose).

Please contact us at editor@informaticsglobal.com for permissions related to commercial use of the article(s).

Crossref
Scopus
Google Scholar
Europe PMC

 

References

Singh, D. and Chaudhuri, P.K. A review on phytochemical and pharmacological properties of Holy basil (Ocimum sanctum L.). Indust. Crop. Prod., 2018, 118, 367-382. https://doi.org/10.1016/j.indcrop.2018.03.048 DOI: https://doi.org/10.1016/j.indcrop.2018.03.048

Cao, H., Chai, T.T.X., Wang, M.F.B., Morais Braga, Yang, J.H., Wong, F.C., Yao, Cao, H.J., Cornara, L., Burlando, B., Wang, Y., Xiao, J. and Coutinho, H.D.M. Phytochemicals from fern species: Potential for medicine applications. Phytochem. Rev., 2017, 16, 379-440. https://doi.org/10.1007/s11101-016-9488-7 DOI: https://doi.org/10.1007/s11101-016-9488-7

Zhao,C., Yang,C.F., Liu, B., Lin,L., Sarker,S.D., Nahar,L., Yu, H.,Cao,H. and Xiao, J.B. Bioactive compounds from marine macroalgae and their hypoglycemic benefits. Tr. Fd. Sci. Technol., 2018, 72, 1-12. https://doi.org/10.1016/j.tifs.2017.12.001 DOI: https://doi.org/10.1016/j.tifs.2017.12.001

Xiao, J.B. Dietary flavonoid aglycones and their glycosides: Which show better biological significance? Cri. Rev. Fd. Sci. Nutr., 2017, 57, 1874-1905.

Young, I.S. and Woodside, J.V. Antioxidants in health and disease. J. Clin. Pathol., 2001, 54, 176-186. https://doi.org/10.1136/jcp.54.3.176 DOI: https://doi.org/10.1136/jcp.54.3.176

Neha, K., Haider, M.R., Pathak, A. and Yar, M.S. Medicinal prospects of antioxidants: A review. Eur. J. Med. Chem., 2019, 178, 687-704. https://doi.org/10.1016/j.ejmech.2019.06.010 DOI: https://doi.org/10.1016/j.ejmech.2019.06.010

Sofia C. Lourenço, Margarida Moldão-Martins and Vítor D. Alves. Antioxidants of natural plant origins: From sources to food industry applications. Molec., 2019, 24, 4132 https://doi.org/10.3390/molecules24224132 DOI: https://doi.org/10.3390/molecules24224132

Jiménez-González, F.J., Veloza, L.A. and Sepúlveda-Arias, J.C. Anti-infectious activity in plants of the genus Tabebuia. Univ Sci., 2013, 18, 257-267. https://doi.org/10.11144/Javeriana.SC18-3.aapg DOI: https://doi.org/10.11144/Javeriana.SC18-3.aapg

Brand-williams, W., Cuvelier, M.E. and Berset, C. Use of free radical method to evaluate antioxidant activity. Lebensmittel Wissenschaft and Technol., 1995, 28, 25-30. https://doi.org/10.1016/S0023-6438(95)80008-5 DOI: https://doi.org/10.1016/S0023-6438(95)80008-5

Shirwaikar Annie, Rajendran, K. and Kumar Dinesh. In-vitro antioxidant studies of Annona squamosa. Ind. J. Experim. Biol., 2004, 142, 803.

Klein, S.M., Cohen, G. and Cederbaum, A.I. Production of formaldehyde during metabolism of dimethyl sulphoxide by hydroxyl radical generating system. Biochem., 1991, 20, 6006-6012. https://doi.org/10.1021/bi00524a013 DOI: https://doi.org/10.1021/bi00524a013

Y?ld?r?m, A., Oktay, M.V. and Bilalog? lu. The antioxidant activities of the leaves of Cydonia vulgaris. Turk. J. Med. Sci., 2001, 31, 23-27.

Shirwaikar Annie and somashekar, A.P. Anti-inflammatory activity and free radical scavenging studies of Aristolochia bracteolate lam. Ind. J. pharm. Sci., 2003, 65, 68.

Sreejayan, N. and Rao, M.N.A. (x). Nitric oxide scavenging by curcuminoids. J. Pharm. Pharmacol., 2003, 49, 105. https://doi.org/10.1111/j.2042-7158.1997.tb06761.x DOI: https://doi.org/10.1111/j.2042-7158.1997.tb06761.x

Lu, Y.R. and Yeap Foo, L. Antioxidant activities of polyphenols from sage (Salvia officinalis). Fd. Chem., 2001, 75, 197-202. https://doi.org/10.1016/S0308-8146(01)00198-4 DOI: https://doi.org/10.1016/S0308-8146(01)00198-4

Porto, C.D., Calligaris, S., Celloti, E. and Nicoli, M.C. Antiradical properties of commercial cognacs assessed by the DPPH test. J. Agric. Fd. Chem., 2000, 48, 4241-4245. https://doi.org/10.1021/jf000167b DOI: https://doi.org/10.1021/jf000167b

Soares, J.R., Dinis, T.C.P., Cunha, A.P. and Almeida, L.M. Antioxidant activities of some extracts of Thymus zygi. Free Radic. Res., 1997, 26, 469-478. https://doi.org/10.3109/10715769709084484 DOI: https://doi.org/10.3109/10715769709084484

Rajani Kanta Sahu, Manoranjan Kar and Rasmirani Routray. DPPH free radical scavenging activity of some leafy vegetables used by Tribals of Odisha, India. J. Med. Plan. Stud., 2013, 1, 21-27.

Mayank Gangwar, Manish Kumar Gautam, Amit Kumar Sharma, Yamini, B., Tripathi, R., Goel, K. and Gopal Nath. Antioxidant capacity and radical scavenging effect of polyphenol rich Mallotus philippenensis fruit extract on human erythrocytes: An in vitro study. The Sci. Worl. J., 2014, 2014, 279451. https://doi.org/10.1155/2014/279451 DOI: https://doi.org/10.1155/2014/279451

Lalhminghlui and Jagetia, G.C. Evaluation of the free-radical scavenging and antioxidant activities of Chilauni, Schima wallichii Korth in vitro. Future Science OA, 2018, 4, FSO272. https://doi.org/10.4155/fsoa-2017-0086 DOI: https://doi.org/10.4155/fsoa-2017-0086

Halliwell, B. Oxidants and human disease: Some new concepts. FASEB J., 1987, 1, 358-364. https://doi.org/10.1096/fasebj.1.5.2824268 DOI: https://doi.org/10.1096/fasebj.1.5.2824268

Yang, X., Yan, F., Huang, S. and Fu, C. Antioxidant activities of fractions from long a pericarp, Fd. Sci. Technol., 2014, 34, 341-345. https://doi.org/10.1590/S0101-20612014005000034 DOI: https://doi.org/10.1590/S0101-20612014005000034

Irshad, Md., Zafaryab, Md., Man Singh, Moshahid, M. and Rizvi1, A. Comparative analysis of the antioxidant activity of cassia fistula extracts. Int. J. Med. Chem., 2012, 2012, 1-7. https://doi.org/10.1155/2012/157125 DOI: https://doi.org/10.1155/2012/157125

Jayanthi P. and Lalitha, P. Reducing power of the solvent extracts of Eichhornia crassipes (Mart.) Solms. Int. J. Pharm. Pharmac. Sci., 2011, 3, 126-128.

Lata, H. and Ahuja, G.K. Role of free radicals in health and disease. Ind. J. Physiol. Allied Sci., 2003, 57, 124-128.

Ialenti, Moncada, S. and Di Rosa, M. Modulation of adjuvant arthritis by endogenous nitric oxide. Br. J. Pharmacol., 1993, 110, 701-705. https://doi.org/10.1111/j.1476-5381.1993.tb13868.x DOI: https://doi.org/10.1111/j.1476-5381.1993.tb13868.x

Rozina Parul, Kumar Kundu and Pijush Saha. In vitro nitric oxide scavenging activity of methanol extracts of three Bangladeshi medicinal plants. The Pharma. Innov. J., 2013, 1, 83-88.