Evaluation of Memory and Cognition Enhancing Activity of Glycerrhiza glabra Linn. Formulation Along with Yoga in Teenage (13-16 years) Students

Jump To References Section

Authors

  • Mrudul Chitrakar
     School of Ayurveda, DY Patil Deemed to be University, Navi Mumbai - 400706, Maharashtra ,IN ORCID logo https://orcid.org/0000-0002-2618-8860
  • Supriya Bhalerao
     IRSHA, Bharati Vidyapeeth Deemed to be University, Pune – 411030, Maharashtra ,IN
  • Vinay Pawar
     School of Ayurveda, DY Patil Deemed to be University, Navi Mumbai - 400706, Maharashtra ,IN
  • Vedvati Bhapkar
     School of Ayurveda, DY Patil Deemed to be University, Navi Mumbai - 400706, Maharashtra ,IN

DOI:

https://doi.org/10.18311/jnr/2023/29523

Keywords:

Intelligence, Medhya Rasayana, Pranayama, Shavasana, Yashtimadhu
Rasayana

Abstract

Yashtimadhu (Glycyrrhiza glabra Linn.) is one of the important neuro-nutrient herbs (Medhya Rasayana) mentioned in Ayurveda classics. Also, its usefulness in memory and cognition has been shown in many studies. Yoga, a part of the rich Indian heritage has also shown promising results in the memory enhancement of children and adults. Thus, a study was planned to assess the efficacy of their combined schedule in teenage students. Glycyrrhiza glabra Linn. was converted into an herbal formulation ‘Yastimadhu Kalpa’ (YK) as per principles of Ayurveda pharmaceutics. The objective of this study was to evaluate the effect of YK and Yoga schedules on the memory and cognitive performance of teenage (13-16 years old) students. In this open-labeled, randomized, placebo-controlled study, 100 assenting healthy students between 13-16 years of age were enrolled and randomized into trial and control groups, after obtaining EC approval and parent consent. Those in the trial group received YK and Yoga, while control group participants received a placebo (Ragi malt) and Yoga. The YK and placebo were to be taken with cow milk in the morning. A 30-minute Yoga schedule was also taught to them. The duration of treatment was of 90 days. Effect on memory and cognition was assessed by using cognitive ability and mental ability tests devised by Jnana-Prabodhini’s Institute of Psychology, Pune. These assessments were done on randomization visits (Day 0) and end-of-study visits (Day 90). Appropriate statistical tests were applied to the data to obtain results. Both groups showed significant improvement in cognition and memory after 90 days of treatment duration. However, YK group showed more significant improvement in cognition of figural classes and cognition of figural system in cognitive ability and memory of figural transformations, the memory of symbolic transformations, total memory, and mental ability among memory test parameters when compared to the control group. The inclusion of a Yoga schedule in both groups was found to be effective in the improvement of memory and cognition. YK (formulation of Glycyrrhiza glabra Linn.) along with Yoga can be used in children to enhance their memory and cognition.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Downloads

Published

2023-03-23

How to Cite

Chitrakar, M., Bhalerao, S., Pawar, V., & Bhapkar, V. (2023). Evaluation of Memory and Cognition Enhancing Activity of <i>Glycerrhiza glabra</i> Linn. Formulation Along with Yoga in Teenage (13-16 years) Students. Journal of Natural Remedies, 23(1), 255–262. https://doi.org/10.18311/jnr/2023/29523

Issue

Volume 23, Issue 1, January 2023

Section

Short Communication

License

Copyright (c) 2023 Mrudul Chitrakar, Supriya Bhalerao, Vedvati Bhapkar, Vinay Pawar

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Crossref
Scopus
Google Scholar
Europe PMC
Received 2022-02-09
Accepted 2023-03-23
Published 2023-03-23

 

References

English Dictionary. https://dictionary.englishtest.info/ browse/emory (accessed February 07, 2022).

What is Psychology? NCERT Textbook; 2019-20. https:// ncert.nic.in/textbook/pdf/kepy101.pdf (accessed May 21, 2021).

Donnelly JE, Hillman CH, Castelli D, Etnier JL, Lee S, Tomporowski P, et al. Physical Activity, Fitness, Cognitive Function, and Academic Achievement in Children: A Systematic Review. Medicine and science in sports and exercise. 2016; 48(6):1197-1222. https://doi.org/10.1249/ MSS.0000000000000901

Shukla V, Triparhi R (rev. 2nd ed.). Charaka Samhita with ‘Vaidyamanorama’ Hindi Commentary, Chikitsa Sthana; Rasayana Chikitsa: chapter 1/1, verse 8. Delhi: Chaukhamba Sanskrit Pratishthan. 2004; 376.

Kulkarni R, Girish KJ, Kumar A. Nootropic herbs (Medhya Rasayana) in Ayurveda: An update. Pharmacognosy Reviews. 2012; 6(12):147-153. https://doi.org/10.4103/0973- 7847.99949

Ray S, Ray A. Medhya Rasayanas in brain function and disease. Med Chem. 2015; 5:505-511. https://doi. org/10.4172/2161-0444.1000309

Shukla V, Triparhi R, editor (rev. 2nd ed.). Charaka Samhita with ‘Vaidyamanorama’ Hindi Commentary, Chikitsa Sthana; Rasayana Chikitsa: chapter 1/1, verse 31. Delhi: Chaukhamba Sanskrit Pratishthan, 2004; 385.

Chakravarthi KK, Avadhani R. Beneficial effect of aqueous root extract of Glycyrrhiza glabra on learning and memory using different behavioral models: An experimental study. J Natural Sci, Biology and Med. 2013; 4(2):420-425. https:// doi.org/10.4103/0976-9668.117025

Cho MJ, Kim JH, Park CH, Lee AY, Shin YS, Lee JH, Park CG, Cho EJ. Comparison of the effect of three licorice varieties on cognitive improvement via an amelioration of neuroinflammation in lipopolysaccharide-induced mice. Nutrition Research and Practice. 2018; 12(3):191-198. https://doi.org/10.4162/nrp.2018.12.3.191

Tripathi B, Pandey G, editor (3rd ed.). Charak Samhita, Sutra sthan; Khuddak chatushpad: chapter 9; verse 7, Varanasi: Chaukhambha Surbharati Prakashan. 1994.

Chitrakar MY. Formulation and standardization of Yashtimadhu Kalpa (Granule): A novel Medhya Rasayana. J Ayurveda. 2021; 15:68-72.

Woodyard C. Exploring the therapeutic effects of yoga and its ability to increase quality of life. International Journal of Yoga. 2011; 4(2):49-54. https://doi.org/10.4103/0973- 6131.85485

Felver JC, Butzer B, Olson KJ, Smith IM, Khalsa, S. B. Yoga in public school improves adolescent mood and affect. Contemporary School Psychology. 2015; 19(3):184-192. https://doi.org/10.1007/s40688-014-0031-9

Gothe NP, Khan I, Hayes J, Erlenbach E, Damoiseaux, J. S. Yoga effects on brain health: A systematic review of the current literature. Brain Plasticity. 2019; 5(1):105-122. https://doi.org/10.3233/BPL-190084

Chitrakar MY. Formulation and standardization of Yashtimadhu Kalpa (Granule): A novel Medhya Rasayana. J Ayurveda. 2021; 15:68-72.

Gadre S, Nirgudkar S, Garde R, Watve S. JPIP tests of mental ability manual. Jnana Prabodhini’s Institute of Psychology; 2013. https://jpip.org/wp-content/uploads/2019/02/ giftedness_review.pdf

Nangia, D, Malhotra, R. Yoga, cognition and mental health. JIAAP. 2012; 38:262-269.

Chamoli V, Badoni, A, Bahuguna N, Joshi N. Finger millet (Eluesine coracana): Nutritional status, health benefits and processing status- A review. J Pharmacognosy and Phytochemistry. 2018; SP5:80-83.

Paradkar HS, editor (reprint 1st ed.). Ashtanga Hrudaya of Vagbhata with Sarvangasundara Commentary by Arundatta and Ayurveda rasayana commentary by Hemadri, Sootra Sthana; Doshabhediya: chapter 12, verse 13. Varanasi: Chaukhamba Surabharati Prakashana. 2004; 248.

Singh N, Bhalla M, de Jager P, Gilca M. An overview on Ashwagandha: A Rasayana (rejuvenator) of Ayurveda. AJTCAM. 2011; 8(5 Suppl):208-213. https://doi. org/10.4314/ajtcam.v8i5S.9

Parle M, Dhingra D, Kulkarni SK. Memory-strengthening activity of Glycyrrhiza glabra in exteroceptive and interoceptive behavioral models. J Med Food. 2004 Winter; 7(4):462-6. https://doi.org/10.1089/jmf.2004.7.462

Pastorino G, Cornara L, Soares S, Rodrigues F, Oliveira, M. (2018). Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review. PTR. 2018; 32(12):2323-2339. https://doi.org/10.1002/ptr.6178

Chitrakar MY, Kudale SS, Deshmukh MP, Budhrani AB. Modulation and validation of Yashtimadhu Kalpa (formulated from Glycyrrhiza glabra) as Medhya Rasayana: A neuro-nutrient. Inter J Res in Pharma Sci. 2020; 11(SPL4):2655-2661. https://doi.org/10.26452/ijrps. v11iSPL4.4536

Chitrakar MY, Deshmukh MP, Budhrani AB, Ingle SS. Evaluation of Yashtimadhu Kalpa formulation as neuronutrient for learning and memory improvement in experimental animals. Inter J Res in Pharma Sci. 2020; 11(SPL4):2564-2569. https://doi.org/10.26452/ijrps. v11iSPL4.4513