Studies and Enhancement of Natural Bioactive Compounds Content through Media Optimization

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Authors

  • Moti Lal
     Department of Biotechnology, School of Sciences (SOS), ITM University, Gwalior – 474001, Madhya Pradesh ,IN
  • Neelam
     Department of Microbiology, School of Sciences (SOS), ITM University, Gwalior – 474001, Madhya Pradesh ,IN
  • Santosh Kumar
     Department of Biotechnology, School of Sciences (SOS), ITM University, Gwalior – 474001, Madhya Pradesh ,IN
  • Nem Kumar Jain
     Department of Pharmacology, School of Pharmacy, ITM University, Gwalior – 474001, Madhya Pradesh ,IN
  • Akshay Singh Sengar
     Department of Food Tech, School of Sciences (SOS), ITM University, Gwalior – 474001, Madhya Pradesh ,IN
  • Varsha Chauhan
     Department of Biotechnology, School of Sciences (SOS), ITM University, Gwalior – 474001, Madhya Pradesh ,IN
  • Swati Rathore
     Department of Biotechnology, School of Sciences (SOS), ITM University, Gwalior – 474001, Madhya Pradesh ,IN
  • Sunena Bamoriya
     Department of Biotechnology, School of Sciences (SOS), ITM University, Gwalior – 474001, Madhya Pradesh ,IN

DOI:

https://doi.org/10.18311/jnr/2024/35119

Keywords:

Antimicrobial Properties, Media Optimization, Scanning of Electron Microscopy, Secondary Bioactive Metabolites

Abstract

In these studies, endophyte bacteria were isolated from a medicinal plant root of Adhathoda beddomei (adosa). The antimicrobial activity was demonstrated against different pathogenic and nonpathogenic bacteria. Identification of endophytes was done based on external morphological characteristics with the help of a Scanning Electron Microscope (SEM). another challenging problem in this regard is that the efficiency of the endophytic bacteria to produce bioactive compounds is not as high as expected because, in many previous works in literature, it has been reported that yields are generally meagre. Through this study, we have tried to enhance the production of bioactive metabolites using media optimization and Resonance Surface Methodology (RSM). These are generally from µg/l to less than mg/l and are therefore not yet appropriate for fermentative production on an industrial level.

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Published

2024-05-01

How to Cite

Lal, M., Neelam, Kumar, S., Jain, N. K., Sengar, A. S., Chauhan, V., Rathore, S., & Bamoriya, S. (2024). Studies and Enhancement of Natural Bioactive Compounds Content through Media Optimization. Journal of Natural Remedies, 24(5), 1141–1151. https://doi.org/10.18311/jnr/2024/35119

Issue

Volume 24, Issue 5, May 2024

Section

Short Communication

Categories

License

Copyright (c) 2024 Moti Lal, Neelam, Santosh Kumar, Nem Kumar Jain, Akshay Singh Sengar, Varsha Chauhan, Swati Rathore, Sunena Bamoriya (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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Europe PMC
Received 2023-11-21
Accepted 2024-02-23
Published 2024-05-01

 

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