Hypoglycemic Properties of Ficus glomerata Fruits in Alloxan-Induced Diabetic Rats

Abstract

Objective: To study the hypoglycaemic properties of Ficus glomerata fruits in alloxan induced diabetic rats. Materials and methods: Petroleum ether, benzene, chloroform, ethanol and aqueous extracts of F. glomerata fruits were screened for hypoglycemic properties in alloxan-induced diabetic rats. The effect was assessed by blood glucose, serum cholesterol, serum urea and serum triglyceride levels. Oral doses of petroleum ether extracts of 250 mg/kg body weight produced significant lowering of blood sugar, serum cholesterol, serum urea and serum triglyceride levels in alloxan-induced diabetic treated rats. The hypoglycemic effects were compared with those of glibenclamide. Conclusion: The present study shows that petroleum ether extracts of fruits of F. glomerata produce better hypoglycemic actions compared to other extracts.