Bio-sourced Hydroxyapatite is better bioactive than its synthetic grade: A comparative assessment of Ti and Zn doped Hydroxyapatite derived from Bio and synthetic sources

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Authors

  • Dalia Acharjee
     School of Bio-Science and Engineering Jadavpur University, Kolkata - 700032, West Bengal ,IN
  • Sujan Krishna Samanta
     Department of Biomedical Engineering, Netaji Subhash Engineering College, Technocity, Garia, Kolkata - 700152, West Bengal ,IN
  • Sourav Debnath
     Department of Electrical and Electronics Engineering, Swami Vivekananda Institute of Science and Technology, Kolkata - 700145, West Bengal ,IN
  • Sukumar Roy
     Department of Biomedical Engineering, Netaji Subhash Engineering College, Technocity, Garia, Kolkata - 700152, West Bengal ,IN
  • Piyali Basak
     School of Bio-Science and Engineering Jadavpur University, Kolkata - 700032, West Bengal ,IN
  • Samit Kumar Nandi
     Department of Veterinary Surgery and Radiology, WBUAFS, Kolkata - 700037, West Bengal ,IN

DOI:

https://doi.org/10.18311/jmmf/2023/33731

Keywords:

Eggshell Waste, SBF, SEM, XRD

Abstract

To meet everyday food requirements with an ever-increasing population in the world, a huge amount of Eggshell waste is given rise everywhere from household kitchens to various food processing units. Eggshell contains a large amount of calcium compound. In this study, two different kinds of Hydroxyapatite (HAp), one from different laboratory reagents and the other one from eggshell have been synthesized. 3% Titanium and Zinc doped variants have also been made for both kinds of Hydroxyapatite. The prepared powder samples were calcined at 800°C and pellets were formed by applying pressure. A comparative analysis of these two different sourced products has been made by analyzing physical properties (Density, apparent porosity, hardness), a functional group study (FTIR). The elemental configuration of all materials was confirmed by the EDAX study. XRD analysis revealed the lattice parameters of the pure product has been suffered a little bit with the doping agents. SEM images showed a significant amount of porosity and nodular grains of HAp. Cytotoxic analysis and MTT assay established the non-toxic nature of all compounds, In vitro SBF study showed apatite layer formation above the pellet surfaces of different grades and Ti-doped samples gained the maximum amount of apatite.

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Published

2023-12-28

How to Cite

Acharjee, D., Samanta, S. K., Debnath, S., Roy, S., Basak, P., & Nandi, S. K. (2023). Bio-sourced Hydroxyapatite is better bioactive than its synthetic grade: A comparative assessment of Ti and Zn doped Hydroxyapatite derived from Bio and synthetic sources. Journal of Mines, Metals and Fuels, 71(11), 1864–1871. https://doi.org/10.18311/jmmf/2023/33731

Issue

Volume 71, Issue 11, November 2023

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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Europe PMC
Received 2023-05-07
Accepted 2023-11-22
Published 2023-12-28

 

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