Acute High Dose Lithium"‘Induced Exacerbation of Obsessive Compulsive Symptoms

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Authors

  • Shreekantiah Umesh
     ,IN
  • Vinod Kumar Sinha
     ,IN

Keywords:

Glutamate, lithium, obsessive compulsive disorder

Abstract

Obsessive compulsive disorder (OCD) is a chronic neuropsychiatric disorder whose pathophysiology is linked to serotonergic dysfunction. More recently, the role of glutamate has also been posited. Lithium is used as an adjunctive for the treatment of OCD which is found to enhance serotonergic transmission. We present a case of OCD who was on stable dose of sertraline developed exacerbation of obsessive compulsive symptoms with acute high dose of lithium but improved after dose reduction.

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Published

2018-04-26

How to Cite

Umesh, S., & Kumar Sinha, V. (2018). Acute High Dose Lithium"‘Induced Exacerbation of Obsessive Compulsive Symptoms. Toxicology International, 21(2), 222–223. Retrieved from https://informaticsjournals.co.in/index.php/toxi/article/view/21009

Issue

Volume 21, Issue 2, May-Aug 2014

Section

Case Report
Received 2018-04-26
Accepted 2018-04-26
Published 2018-04-26

 

References

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