A Rare Neurological Complication of Acute Organophosphorous Poisoning

Jump To References Section

Authors

  • Balamurali Kalyanam
     ,NA
  • Sarala Narayana
     ,IN
  • Prabhakar Kamarthy
     ,IN

Keywords:

Amantidine, rigidity, extrapyramidal signs, organophosphorous poisoning

Abstract

Organophosphorous (OP) compound poisoning is one of the most common causes for admission to the Medical Intensive Care Unit. The morbidity and mortality associated with OP poisoning is due to the action of the compound at the muscarinic, nicotinic receptors, and the central nervous system. Here is a rare case of extrapyramidal manifestations occurring in the intermediate phase of OP poisoning, use of amantidine led to subsiding of the symptoms.

Downloads

Download data is not yet available.

Downloads

Published

2018-08-09

How to Cite

Kalyanam, B., Narayana, S., & Kamarthy, P. (2018). A Rare Neurological Complication of Acute Organophosphorous Poisoning. Toxicology International, 20(2), 189–191. Retrieved from https://informaticsjournals.co.in/index.php/toxi/article/view/21727

Issue

Volume 20, Issue 2, May - August 2013

Section

Case Report
Received 2018-08-09
Accepted 2018-08-09
Published 2018-08-09

 

References

Pandit V, Seshadri S, Rao SN, Samarasinghe C, Kumar A, Valsalan R. A case of organophosphate poisoning presenting with seizure and unavailable history of parenteral suicide attempt.J Emerg Trauma Shock 2011;4:132"‘4.

Senanayake N, Sanmuganathan PS. Extrapyramidal manifestations complicating organophosphorous insecticide poisoning. Hum Exp Toxicol 1995;14:600"‘4.

Tanima D, Maisnam I, Kundu AK, Saha SP, Ghosh S, Maity A.Atypical central nervous system involvement in acute organophosphorous poisoning. J Assoc Physicians India 2011;59:326"‘7.

Hsieh BH, Deng JF, Ger J, Tsai WJ. Acetylcholinesterase inhibition and the extrapyramidal syndrome: A review of the neurotoxicity of organophosphate. Neurotoxicology 2001;22:423"‘7.

Shahar E, Bentur Y, Bar"‘Joseph G, Cahana A, Hershman E.Extrapyramidal parkinsonism complicating acute organophosphate insecticide poisoning. Pediatr Neurol 2005;33:378"‘82.

Nakamagoe K, Watanabe M, Takeda T, Mizutani T, Tamaoka A.Parkinsonism with organophosphate poisoning. BMJ Case Rep 2009.

Brahmi N, Gueye PN, Thabet H, Kouraichi N, Ben Salah N, Amamou M. Extrapyramidal syndrome as a delayed and reversible complication of acute dichlorvos organophosphate poisoning. Vet Hum Toxicol 2004;46:187"‘9.

Shahar E, Andraws J. Extra"‘pyramidal parkinsonism complicating organophosphate insecticide poisoning. Eur J Paediatr Neurol 2001;5:261"‘4.

Liu H, Yang Y, Yang J, Meng L. Brain injury due to acute organophosphate poisoning: Magnetic resonance imagingmanifestation and pathological characteristics. Nerve Regen Res 2007;2:403.

Müller"‘Vahl KR, Kolbe H, Dengler R. Transient severe parkinsonism after acute organophosphate poisoning. J Neurol Neurosurg Psychiatry 1999;66:253"‘4.

Bhatt MH, Elias MA, Mankodi AK. Acute and reversible parkinsonism due to organophosphate pesticide intoxication: Five cases. Neurology 1999;52:1467"‘71.

Praveen Kumar AS, Subrahmanyam DK. Acute reversible parkinsonism following accidental exposure to organophosphate insecticide. Int J Nutr Pharmacol Neurol Dis 2013;1:70"‘2.