Effect of Monosodium Glutamate on Various Lipid Fractions and Certain Antioxidant Enzymes in Arterial Tissue of Chronic Alcoholic Adult Male Mice

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Authors

  • Kuldip Singh
     ,IN
  • Jaspinder Kaur
     ,IN
  • P. Ahluwalia
     ,IN
  • Jyoti Sharma
     ,IN

Keywords:

Alcohol, lipid peroxidation, monosodium glutamate, oxidative stress and atherosclerosis

Abstract

Oral ingestion of monosodium glutamate (MSG) to chronic alcoholic adult male mice at dose levels of 4 and 8 mg/g body weight for seven consecutive days caused a significant increase in lipid fractions, lipid peroxidation, xanthine oxidase, whereas the levels of superoxide dismutase, catalase, glutathione, and its metabolizing enzymes like glutathione peroxidase and glutathione reductase were significantly decreased in the arterial tissue. These observations suggested that ingestion of MSG to chronic alcoholic animals had no beneficial effect and thereby, could act as an additional factor for the initiation of atherosclerosis.

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Published

2018-08-21

How to Cite

Singh, K., Kaur, J., Ahluwalia, P., & Sharma, J. (2018). Effect of Monosodium Glutamate on Various Lipid Fractions and Certain Antioxidant Enzymes in Arterial Tissue of Chronic Alcoholic Adult Male Mice. Toxicology International, 19(1), 9–14. Retrieved from https://informaticsjournals.co.in/index.php/toxi/article/view/21810

Issue

Volume 19, Issue 1, January- April 2012

Section

Original Research
Received 2018-08-21
Accepted 2018-08-21
Published 2018-08-21

 

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