Incidence and Outcome of Aluminium Phosphide Poisoning Cases Admitted to the Egyptian National Poisoning Centre

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Authors

  • Eman AM. Abdel Rashid
     ,EG
  • Nashwa M. El Mahdy
     ,EG

DOI:

https://doi.org/10.18311/ti/2018/v25i4/23804

Keywords:

Aluminium Phosphide (ALP), Blood Lactate Level, Mortality, Phosphine Gas, Prediction

Abstract

Aluminium Phosphide (ALP) poisoning is one of the major causes of suicidal deaths. It is one of the fatal pesticides. It liberates lethal phosphine gas when it comes in contact either with atmospheric moisture or with hydrochloric acid in the stomach. It causes cellular hypoxia, inhibition of cytochrome c oxidase and formation of highly reactive hydroxyl radicals. The aim of this work was to investigate ALP poisoning-related deaths in the National Egyptian Center of Environmental and Toxicological Research (NECTR), to arouse attention to its use in committing suicide due to its easy availability through the objective data from a sample of acutely poisoned patients admitted to NECTR in Cairo. Management of cases is mainly supportive as there is no specific antidote, causing high mortality rate. Early arrival and proper decontamination, resuscitation, intensive monitoring and supportive therapy may result in good outcome.

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Published

2019-10-22

How to Cite

Abdel Rashid, E. A., & El Mahdy, N. M. (2019). Incidence and Outcome of Aluminium Phosphide Poisoning Cases Admitted to the Egyptian National Poisoning Centre. Toxicology International, 25(4), 213–223. https://doi.org/10.18311/ti/2018/v25i4/23804

Issue

Volume 25, Issue 4, October- December 2018

Section

Articles
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Scopus
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Europe PMC
Received 2019-06-11
Accepted 2019-09-02
Published 2019-10-22

 

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