Role of Natural Polymers in Novel Drug Delivery Systems

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Authors

  • Nirmal Shah
     Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara - 391760, Gujarat ,IN ORCID logo https://orcid.org/0000-0003-1282-937X
  • Ghanshyam Parmar
     Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara - 391760, Gujarat ,IN ORCID logo https://orcid.org/0000-0002-4614-9797
  • Dipti Gohil
     Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara - 391760, Gujarat ,IN
  • Rajesh Maheshwari
     Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara - 391760, Gujarat ,IN ORCID logo https://orcid.org/0000-0002-2658-9517
  • Chintan Aundhia
     Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara - 391760, Gujarat ,IN
  • Sunil Kardani
     Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara - 391760, Gujarat ,IN

DOI:

https://doi.org/10.18311/jnr/2024/42036

Keywords:

Efficient Therapy, Improved Bioavailability, Natural Polymers, Novel Drug Delivery

Abstract

Natural polymers have gained significant attention in the field of drug delivery due to their inherent biocompatibility, biodegradability, and low toxicity. This review article aims to provide a comprehensive overview of the diverse roles that natural polymers play in the development of novel drug delivery systems. Beginning with a classification of natural polymers based on their origin (plant, animal, microbial), we explore their unique characteristics and advantages over synthetic counterparts. The review discusses the pivotal role of natural polymers in formulating various drug delivery systems, including sustained/controlled release formulations, targeted delivery platforms, mucoadhesive systems, and nanotechnology-based approaches. Techniques such as emulsification, ionotropic gelation, coacervation, and electrospinning for natural polymer-based drug delivery are elucidated, highlighting their versatility and applicability across different administration routes. Furthermore, we delve into the diverse applications of natural polymers in drug delivery, encompassing oral, transdermal, ocular, injectable, nasal, buccal, and vaginal delivery routes. Recent advances and innovations in combining natural polymers with synthetic counterparts, incorporating stimuli-responsive properties, and personalized medicine approaches are also explored. Despite the numerous advantages offered by natural polymers, challenges such as variability in polymer properties, standardization issues, scale-up challenges, and regulatory considerations are discussed. The review concludes with future perspectives, highlighting emerging trends and opportunities for further research and development in the field of natural polymer-based drug delivery systems. Overall, this review provides valuable insights into the pivotal role of natural polymers in advancing drug delivery technology, paving the way for safer, more efficient, and patient-friendly therapeutic interventions.

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Published

2024-10-07

How to Cite

Shah, N., Parmar, G., Gohil, D., Maheshwari, R., Aundhia, C., & Kardani, S. (2024). Role of Natural Polymers in Novel Drug Delivery Systems. Journal of Natural Remedies, 24(9), 1923–1934. https://doi.org/10.18311/jnr/2024/42036

Issue

Volume 24, Issue 9, September 2024

Section

Short Review

Categories

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Copyright (c) 2024 Nirmal Shah (Author); Ghanshyam Parmar, Dipti Gohil, Rajesh Maheshwari, Chintan Aundhia, Sunil Kardani

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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Europe PMC
Received 2024-03-13
Accepted 2024-08-12
Published 2024-10-07

 

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