Catechins and Theaflavins: An Overview on Therapeutic Application

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Authors

  • Ashim Kumar Sen
     Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara - 391760, Gujarat ,IN
  • Dhanya B. Sen
     Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara - 391760, Gujarat ,IN ORCID logo http://orcid.org/0000-0001-8871-7396
  • Aarti S. Zanwar
     Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara - 391760, Gujarat ,IN ORCID logo http://orcid.org/0000-0002-9246-9249
  • Ramachandran Balaraman
     Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara - 391760, Gujarat ,IN ORCID logo http://orcid.org/0000-0003-2619-4862
  • Umang Shah
     Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT Campus, Changa, Petlad, Anand, Gujarat - 388421 ,IN
  • Rajesh A. Maheshwari
     Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara - 391760, Gujarat ,IN ORCID logo http://orcid.org/0000-0002-2658-9517

DOI:

https://doi.org/10.18311/jnr/2022/30181

Keywords:

Catechins, Flavonoids, Plants, Secondary Metabolites, Theaflavins

Abstract

Flavonoids are a sort of natural substance which are basically plant secondary metabolites having a polyphenolic structure present in a wide range of food products. Flavonoids have become a vital constituent in nutraceutical, pharmacological, therapeutic, and cosmetic fields. This is owing to their capability to regulate essential cellular enzyme activity along with anti-cancer, anti-oxidative, anti-mutagenic, and anti-inflammatory effects. Through the revelation of a minimal cardiovascular death rate and the deterrence of CHD, research on flavonoids has gotten a boost. The functional mechanisms of flavonoids are still not completely known. Molecular docking and bioinformatics information are also been used to forecast potential flavonoid functions. Flavonoids are divided into several categories. Catechins and Theaflavins (TF’s) are two types of flavonoids that have been discussed in this review. ROS scavenging property of tea catechins and polyphenols have been demonstrated in vitro, and they may also serve as indirect antioxidants via their influence on transcription features and enzyme actions. There are a number of antioxidant polyphenols called collectively as “theaflavins” that are produced during the enzymatic oxidation (sometimes referred to mistakenly as “fermentation”) of black tea leaves by flavan-3-ol condensation Theaflavin-3-gallate, theaflavin-3’-gallate, and theaflavin-3-3’-digallate are the major theaflavins.

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Published

2022-07-30

How to Cite

Kumar Sen, A., Sen, D. B., Zanwar, A. S., Balaraman, R., Shah, U., & Maheshwari, R. A. (2022). Catechins and Theaflavins: An Overview on Therapeutic Application. Journal of Natural Remedies, 22(3), 330–346. https://doi.org/10.18311/jnr/2022/30181

Issue

Volume 22, Issue 3, July 2022

Section

Short Review
Crossref
Scopus
Google Scholar
Europe PMC
Received 2022-05-04
Accepted 2022-06-08
Published 2022-07-30

 

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